Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | NPY4R | P50391 | 3/20 | 0.42 |
| ▸ | NPY1R | P25929 | 2/20 | 0.42 |
| ▸ | NPY2R | P49146 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13311908 | 0.96 | TDP1 (0.61) | TDP1CAPN1FOLH1CNR1CASP3 | |
| SCHEMBL13311789 | 0.94 | TDP1 (0.51) | TDP1CAPN1FOLH1CNR1CASP3 | |
| SCHEMBL13432545 | 0.94 | TDP1 (0.51) | TDP1CAPN1FOLH1CNR1CASP3 | |
| SCHEMBL13311883 | 0.94 | TDP1 (0.57) | TDP1CAPN1FOLH1CASP3CASP1 | |
| SCHEMBL13311913 | 0.92 | TDP1 (0.58) | TDP1CAPN1FOLH1CNR1CASP3 | |
| SCHEMBL13311852 | 0.92 | TDP1 (0.55) | TDP1CAPN1FOLH1CNR1CASP3 | |
| SCHEMBL16327114 | 0.91 | TDP1 (0.58) | TDP1CAPN1FOLH1CASP3CASP1 | |
| SCHEMBL13432796 | 0.90 | TDP1 (0.54) | TDP1CAPN1FOLH1CNR1CASP3 | |
| SCHEMBL14524231 | 0.90 | TDP1 (0.54) | TDP1CAPN1FOLH1CNR1CASP3 | |
| SCHEMBL14524270 | 0.90 | TDP1 (0.54) | TDP1CAPN1FOLH1CNR1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160210-A1 | GUANIDINIUM DELIVERY CARRIERS | NITTO DENKO CORPORATION (JP) | 2010-06-24 | — | — | US | disclosed |
| US-7687603-B2 | Guanidinium delivery carriers | NITTO DENKO CORPORATION (JP) | 2010-03-30 | — | — | US | disclosed |
| US-20070078094-A1 | Guanidinium delivery carriers | NITTO DENKO CORPORATION (JP) | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160210-A1 | GUANIDINIUM DELIVERY CARRIERS | SLC2A9, SLC29A2, SLC2A4 | TDP1 1606/4885CAPN1 2600/4885FOLH1 288/4885 |
| US-20070078094-A1 | Guanidinium delivery carriers | SLC2A9, SLC29A2, SLC2A4 | TDP1 1606/4885CAPN1 2600/4885FOLH1 288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.