Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | IDE | P14735 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13311908 | 0.93 | TDP1 (0.61) | TDP1CAPN1FOLH1MEN1ABL1 | |
| SCHEMBL14524233 | 0.93 | TDP1 (0.54) | TDP1CAPN1FOLH1MEN1ABL1 | |
| SCHEMBL14524270 | 0.93 | TDP1 (0.54) | TDP1CAPN1FOLH1MEN1ABL1 | |
| SCHEMBL13311792 | 0.93 | TDP1 (0.54) | TDP1CAPN1FOLH1MEN1ABL1 | |
| SCHEMBL14524231 | 0.93 | TDP1 (0.54) | TDP1CAPN1FOLH1MEN1ABL1 | |
| SCHEMBL13432796 | 0.93 | TDP1 (0.54) | TDP1CAPN1FOLH1MEN1ABL1 | |
| SCHEMBL13311807 | 0.92 | TDP1 (0.56) | TDP1CAPN1FOLH1MEN1ABL1 | |
| SCHEMBL13311789 | 0.92 | TDP1 (0.51) | TDP1CAPN1FOLH1MEN1ABL1 | |
| SCHEMBL13311812 | 0.92 | TDP1 (0.56) | TDP1CAPN1FOLH1MEN1ABL1 | |
| SCHEMBL13432545 | 0.91 | TDP1 (0.51) | TDP1CAPN1FOLH1MEN1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160210-A1 | GUANIDINIUM DELIVERY CARRIERS | NITTO DENKO CORPORATION (JP) | 2010-06-24 | — | — | US | disclosed |
| US-20100160210-A1 | GUANIDINIUM DELIVERY CARRIERS | NITTO DENKO CORPORATION (JP) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160210-A1 | GUANIDINIUM DELIVERY CARRIERS | SLC2A9, SLC29A2, SLC2A4 | TDP1 1606/4885CAPN1 2600/4885FOLH1 288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.