SCHEMBL1331297

SCHEMBL1331297

CCOC(=O)[13CH2]P(=O)(OCC)OCC

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
MGAM O43451 1/20 0.48
GAA P10253 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
PPARD Q03181 1/20 0.46
ALDH1A1 P00352 5/20 0.44
TRPA1 O75762 1/20 0.44
CYP1A2 P05177 1/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALOX15 P16050 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
TP53 P04637 1/20 0.37
SOAT1 P35610 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16047 1.00 TSHR (0.48) TSHRMGAMGAASIMGAM2
SCHEMBL18759661 1.00 TSHR (0.48) TSHRMGAMGAASIMGAM2
SCHEMBL31218556 0.94 TSHR (0.43) TSHRMGAMGAASIMGAM2
SCHEMBL15438304 0.92 TSHR (0.46) TSHRMGAMGAASIMGAM2
Ethyl Acetate SCHEMBL30306639 0.92 ALDH1A1 (0.54) TSHRMGAMGAASIMGAM2
SCHEMBL2242036 0.90 TSHR (0.40) TSHRMGAMGAASIMGAM2
SCHEMBL2238293 0.90 TSHR (0.43) TSHRMGAMGAASIMGAM2
SCHEMBL6669420 0.89 TSHR (0.46) TSHRMGAMGAASIMGAM2
SCHEMBL20503413 0.89 TSHR (0.39) TSHRMGAMGAASIMGAM2
SCHEMBL2237631 0.87 CYP3A4 (0.44) TSHRMGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9673030-B2 Computer readable storage mediums, methods and systems for normalizing chemical profiles in biological or medical samples detected by mass spectrometry EMORY UNIVERSITY (US) 2017-06-06 US disclosed
US-20110282587-A1 COMPUTER READABLE STORAGE MEDIUMS, METHODS AND SYSTEMS FOR NORMALIZING CHEMICAL PROFILES IN BIOLOGICAL OR MEDICAL SAMPLES DETECTED BY MASS SPECTROMETRY EMORY UNIVERSITY (US) 2011-11-17 US disclosed