Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 2/20 | 0.50 |
| ▸ | CPA2 | P48052 | 2/20 | 0.50 |
| ▸ | CPA4 | Q9UI42 | 2/20 | 0.50 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.49 |
| ▸ | CHRNG | P07510 | 3/20 | 0.49 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.49 |
| ▸ | CHRND | Q07001 | 3/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13313861 | 1.00 | CPA1 (0.50) | CPA1CPA2CPA4CHRNA1CHRNG | |
| SCHEMBL13313880 | 0.95 | CA2 (0.52) | ACECTSSCTSKCA12CA1 | |
| SCHEMBL13313863 | 0.95 | CA2 (0.52) | ACECTSSCTSKCA12CA1 | |
| SCHEMBL13313865 | 0.95 | CA2 (0.52) | ACECTSSCTSKCA12CA1 | |
| SCHEMBL13313884 | 0.95 | CA2 (0.52) | ACECTSSCTSKCA12CA1 | |
| SCHEMBL13625030 | 0.95 | CPA1 (0.53) | CPA1CPA2CPA4CHRNA1CHRNG | |
| SCHEMBL13625035 | 0.95 | CPA1 (0.53) | CPA1CPA2CPA4CHRNA1CHRNG | |
| SCHEMBL13313862 | 0.92 | SYK (0.49) | CPA1CPA2CPA4ACEGRIA1 | |
| SCHEMBL13038592 | 0.92 | SYK (0.49) | CPA1CPA2CPA4ACEGRIA1 | |
| SCHEMBL13625015 | 0.88 | CPA1 (0.47) | CPA1CPA2CPA4CHRNA1CHRNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100136063-A1 | Immunotherapy for Treatment of Amyloid-Related Disorders Using Encapsulated Beta-Amyloid Peptides | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-06-03 | — | — | US | disclosed |
| US-7618944-B2 | Encapsulating in micelle which is a block copolymer containing hydrophilic and hydrophobic blocks | INTEZYNE TECHNOLOGIES, INC. (US) | 2009-11-17 | — | — | US | disclosed |
| US-20080274965-A1 | ENCAPSULATED AMYLOID-BETA PEPTIDES | INTEZYNE TECHNOLOGIES, INC. (US) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100136063-A1 | Immunotherapy for Treatment of Amyloid-Related Disorders Using Encapsulated Beta-Amyloid Peptides | IAPP, APP, TTR | CPA1 778/4885CPA2 852/4885CPA4 694/4885 |
| US-20080274965-A1 | ENCAPSULATED AMYLOID-BETA PEPTIDES | IAPP, APP, TTR | CPA1 262/4885CPA2 260/4885CPA4 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.