SCHEMBL13314437

SCHEMBL13314437

C#CCOC(=O)C(N)CCCN

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.42
SLC1A3 P43003 1/20 0.37
SLC1A2 P43004 1/20 0.37
SLC1A1 P43005 1/20 0.37
DPP7 Q9UHL4 6/20 0.35
DPP4 P27487 3/20 0.35
NPC1 O15118 1/20 0.34
DPP8 Q6V1X1 2/20 0.33
DPP9 Q86TI2 2/20 0.33
CPB2 Q96IY4 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
GNAI3 P08754 1/20 0.32
GNAO1 P09471 1/20 0.32
GNAI1 P63096 1/20 0.32
GSTP1 P09211 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13314435 0.95 GSR (0.50) GSRSLC1A3SLC1A2SLC1A1DPP7
SCHEMBL419142 0.95 GSR (0.50) GSRSLC1A3SLC1A2SLC1A1DPP7
SCHEMBL29410188 0.84 GSR (0.46) GSRSLC1A3SLC1A2SLC1A1TSHR
SCHEMBL28945063 0.84 GSR (0.46) GSRSLC1A3SLC1A2SLC1A1TSHR
SCHEMBL9576146 0.79 GSR (0.44) GSRDPP7DPP4DPP8DPP9
SCHEMBL21590082 0.79 SLC1A3 (0.38) SLC1A3SLC1A2SLC1A1NPC1CA12
SCHEMBL21590074 0.79 SLC1A3 (0.38) SLC1A3SLC1A2SLC1A1NPC1CA12
SCHEMBL9576147 0.79 GSR (0.44) GSRDPP7DPP4DPP8DPP9
SCHEMBL28747119 0.78 GSR (0.50) GSRDPP7DPP4DPP8DPP9
SCHEMBL1661419 0.78 GSTP1 (0.41) GSRSLC1A3SLC1A2SLC1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170198283-A1 TEMPLATED MOLECULES AND METHODS FOR USING SUCH MOLECULES NUEVOLUTION A/S (DK) 2017-07-13 US disclosed
US-9688980-B2 Templated molecules and methods for using such molecules NUEVOLUTION (DK) 2017-06-27 US disclosed
US-20150315567-A1 TEMPLATED MOLECULES AND METHODS FOR USING SUCH MOLECULES NUEVOLUTION A/S (DK) 2015-11-05 US disclosed
US-7727713-B2 Templated molecules and methods for using such molecules NUEVOLUTION A/S (DK) 2010-06-01 US disclosed