SCHEMBL9576147

SCHEMBL9576147

C#COC(=O)[C@H](N)CCCN

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.44
DPP7 Q9UHL4 11/20 0.36
DPP4 P27487 6/20 0.36
DPP8 Q6V1X1 5/20 0.34
DPP9 Q86TI2 4/20 0.34
CPB2 Q96IY4 2/20 0.33
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33
RNPEP Q9H4A4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9576146 1.00 GSR (0.44) GSRDPP7DPP4DPP8DPP9
SCHEMBL3275066 0.94 GSR (0.52) GSRDPP7DPP4DPP8DPP9
SCHEMBL20945414 0.94 GSR (0.52) GSRDPP7DPP4DPP8DPP9
Hydrochloric Acid SCHEMBL20945380 0.93 GSR (0.50) GSRDPP7DPP4DPP8DPP9
SCHEMBL29517685 0.81 GSR (0.44) GSRDPP7DPP4DPP8DPP9
SCHEMBL13314437 0.79 GSR (0.42) GSRDPP7DPP4DPP8DPP9
SCHEMBL1537223 0.77 GSR (0.52) GSRDPP7DPP4DPP8DPP9
SCHEMBL29075853 0.77 GSR (0.52) GSRDPP7DPP4DPP8DPP9
SCHEMBL997560 0.77 GSR (0.52) GSRDPP7DPP4DPP8DPP9
SCHEMBL28179884 0.77 CYP2D6 (0.38) GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0543949-A4 ENZYMIC ALTERATION OF HAIR GROWTH 1993-08-04 EP claimed
EP-0543949-A1 ENZYMIC ALTERATION OF HAIR GROWTH. HANDELMAN JOSEPH H (US) 1993-06-02 EP claimed
WO-1992003140-A1 ENZYMIC ALTERATION OF HAIR GROWTH HANDELMAN JOSEPH H (US) 1992-03-05 WO claimed
EP-0198893-A4 HAIR GROWTH MODIFICATION. HANDELMAN JOSEPH H (US) 1988-05-10 EP disclosed
EP-0198893-A1 HAIR GROWTH MODIFICATION. HANDELMAN JOSEPH H (US) 1986-10-29 EP disclosed
WO-1986002269-A1 HAIR GROWTH MODIFICATION HANDELMAN, JOSEPH, H. (US) 1986-04-24 WO disclosed