Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 4/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3294905 | 0.79 | CYP3A4 (0.38) | CYP3A4FDPSARTSHRLMNA | |
| SCHEMBL30451536 | 0.75 | FDPS (0.36) | CYP3A4FDPSARTSHRLMNA | |
| SCHEMBL1304909 | 0.74 | FDPS (0.38) | CYP3A4FDPSARTSHRLMNA | |
| SCHEMBL31030327 | 0.74 | FDPS (0.37) | CYP3A4FDPSARTSHRNOS1 | |
| SCHEMBL21996407 | 0.72 | FDPS (0.38) | CYP3A4FDPSARTSHRNOS1 | |
| SCHEMBL29268091 | 0.71 | AR (0.37) | CYP3A4FDPSARTSHRLMNA | |
| SCHEMBL1444746 | 0.71 | FDPS (0.40) | CYP3A4FDPSARTSHRNOS1 | |
| SCHEMBL14529594 | 0.71 | FDPS (0.40) | CYP3A4FDPSARTSHRLMNA | |
| SCHEMBL30171197 | 0.70 | AR (0.46) | CYP3A4FDPSARTSHRLMNA | |
| SCHEMBL29699401 | 0.69 | FDPS (0.39) | CYP3A4FDPSARTSHRNOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737277-B2 | Electroluminescent bis-cyclometalled iridium compounds and devices made with such compounds | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-15 | — | — | US | disclosed |