Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13316654 | 0.82 | KLKB1 (0.33) | KLKB1SLC22A12 | |
| SCHEMBL13316652 | 0.77 | — | — | |
| SCHEMBL13349621 | 0.75 | — | — | |
| SCHEMBL13349710 | 0.73 | CXCR2 (0.32) | KLKB1SLC22A12 | |
| SCHEMBL13316641 | 0.73 | CCNT1 (0.34) | KLKB1SLC22A12 | |
| SCHEMBL13316618 | 0.71 | — | — | |
| SCHEMBL13316614 | 0.70 | CYP3A4 (0.42) | — | |
| SCHEMBL13349598 | 0.69 | CXCR2 (0.32) | KLKB1SLC22A12 | |
| SCHEMBL13349624 | 0.69 | — | — | |
| SCHEMBL13349597 | 0.68 | CXCR2 (0.34) | KLKB1SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745459-B2 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-06-29 | — | — | US | disclosed |
| US-7745459-B2 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-06-29 | — | — | US | disclosed |