Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 7/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | CFD | P00746 | 2/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3626742 | 0.99 | METTL3 (0.39) | METTL3CMA1NOTUMPDE4APDE4B | |
| SCHEMBL3628451 | 0.91 | METTL3 (0.42) | METTL3CMA1NOTUMPDE4APDE4B | |
| SCHEMBL3624155 | 0.91 | METTL3 (0.42) | METTL3CMA1NOTUMPDE4APDE4B | |
| SCHEMBL3625171 | 0.90 | METTL3 (0.39) | METTL3CMA1NOTUMPDE4APDE4B | |
| SCHEMBL3625761 | 0.90 | METTL3 (0.40) | METTL3CMA1NOTUMPDE4APDE4B | |
| SCHEMBL3623481 | 0.89 | METTL3 (0.41) | METTL3CMA1NOTUMPDE4APDE4B | |
| SCHEMBL3623959 | 0.89 | METTL3 (0.41) | METTL3CMA1NOTUMPDE4APDE4B | |
| SCHEMBL3621807 | 0.88 | METTL3 (0.38) | METTL3CMA1NOTUMPDE4APDE4B | |
| SCHEMBL3623800 | 0.88 | METTL3 (0.41) | METTL3CMA1NOTUMPDE4APDE4B | |
| SCHEMBL3625003 | 0.88 | METTL3 (0.41) | METTL3CMA1NOTUMPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745459-B2 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-06-29 | — | — | US | disclosed |
| US-7745459-B2 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-06-29 | — | — | US | disclosed |