Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13317251 | 1.00 | POLB (0.45) | POLBNPSR1HTTMEN1KMT2A | |
| SCHEMBL3623624 | 0.92 | NR1H3 (0.53) | POLBNPSR1HTTMEN1KMT2A | |
| SCHEMBL3628348 | 0.92 | NR1H3 (0.53) | POLBNPSR1HTTMEN1KMT2A | |
| SCHEMBL3623627 | 0.92 | NR1H3 (0.53) | POLBNPSR1HTTMEN1KMT2A | |
| SCHEMBL13317244 | 0.87 | MEN1 (0.47) | NPSR1HTTMEN1KMT2ANR1H3 | |
| SCHEMBL13317252 | 0.87 | MEN1 (0.47) | NPSR1HTTMEN1KMT2ANR1H3 | |
| SCHEMBL13317250 | 0.87 | MEN1 (0.47) | NPSR1HTTMEN1KMT2ANR1H3 | |
| SCHEMBL13317297 | 0.84 | NPSR1 (0.45) | NPSR1HTTMEN1KMT2ANR1H3 | |
| SCHEMBL13317259 | 0.79 | RAB9A (0.57) | NR1H3ALDH1A1 | |
| SCHEMBL3626532 | 0.79 | NR1H3 (0.56) | NPSR1HTTMEN1KMT2ANR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741317-B2 | LXR modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-06-22 | — | — | US | disclosed |