SCHEMBL133181

SCHEMBL133181

Brn1cccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28014109 0.97
SCHEMBL9464929 0.65 NOS1 (0.38)
SCHEMBL27958769 0.61
SCHEMBL859075 0.61
SCHEMBL6901738 0.61 KCNN4 (0.36)
SCHEMBL25569 0.61
SCHEMBL4760609 0.60
SCHEMBL1375630 0.60 NOS1 (0.35)
SCHEMBL4952 0.60
SCHEMBL3285578 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 985 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-222694709-U Bromopyrazole production system of compound 山东友道化学有限公司 2025-04-01 CN claimed
WO-2024199457-A1 COMPOUND HAVING RING FUSED STRUCTURE, PREPARATION METHOD THEREFOR AND USE THEREOF, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 苏州安赛隆医药科技有限公司 2024-10-03 WO claimed
CN-118724903-A Compound with fused ring structure, its preparation method and use, and pharmaceutical composition and use 苏州安赛隆医药科技有限公司 2024-10-01 CN claimed
US-12030869-B2 5-membered heteroaryl carboxamide compounds for treatment of HBV ASSEMBLY BIOSCIENCES, INC. (US) 2024-07-09 US claimed
US-20240150324-A1 5-Membered Heteroaryl Carboxamide Compounds for Treatment of HBV ASSEMBLY BIOSCIENCES, INC. 2024-05-09 US claimed
CN-117442554-A Liquid preparation of bripirtine 广州汉光药业股份有限公司 2024-01-26 CN claimed
CN-220194960-U High-efficient filter equipment is used in production of evenly crushed bromopyrazole 山东高瑞化工有限公司 2023-12-19 CN claimed
CN-116172984-B Bromopsis oral film-dissolving agent and preparation method thereof 宙晟智维生命科学(上海)有限公司 2023-06-30 CN claimed
CN-116172984-A Bromopsis oral film-dissolving agent and preparation method thereof 宙晟智维生命科学(上海)有限公司 2023-05-30 CN claimed
US-11612614-B2 Isomorphs of Remdesivir and methods for synthesis of same Anzalp Pharmasolutions Pvt. Ltd. (IN) 2023-03-28 US claimed
CN-217549819-U Energy-saving neutralization kettle for producing 4-bromopyrazole 山东高瑞化工有限公司 2022-10-11 CN claimed
CN-217249101-U High-efficient filter equipment is used in bromine pyrazole production 赛乐成尔(武汉)科技有限公司 2022-08-23 CN claimed
US-20210228605-A1 ISOMORPHS OF REMDESIVIR AND METHODS FOR SYNTHESIS OF SAME Anzalp Pharmasolutions Pvt. Ltd. (IN) 2021-07-29 US claimed
US-20210161927-A1 ISOMORPHS OF REMDESIVIR AND METHODS FOR SYNTHESIS OF SAME Anzalp Pharmasolutions Pvt. Ltd. (IN) 2021-06-03 US claimed
CN-111072630-A Preparation method and application of bromopyrazole compound intermediate 东南大学 2020-04-28 CN claimed
CN-103992318-A Pyrazolopyridine compound and preparation method thereof SPHINX SCIENT LAB CORP 2014-08-20 CN claimed
CN-101151268-A Hydrazinocarbonyl-thieno[2,3-c]pyrazoles, preparation method, compositions containing same and use AVENTIS PHARMA SA (FR) 2008-03-26 CN claimed
EP-0973767-A1 INDAZOLES OF CYCLIC UREAS USEFUL AS HIV PROTEASE INHIBITORS Dupont Pharmaceuticals Company (US) 2000-01-26 EP claimed
US-5985867-A TREATING HIV INFECTION DUPONT PHARMACEUTICALS COMPANY (US) 1999-11-16 US claimed
WO-1998043969-A1 INDAZOLES OF CYCLIC UREAS USEFUL AS HIV PROTEASE INHIBITORS DUPONT PHARMACEUTICALS COMPANY (US) 1998-10-08 WO claimed