Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 11/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.53 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13300474 | 1.00 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DRAPGEF3 | |
| SCHEMBL14261185 | 0.92 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DRAPGEF3 | |
| SCHEMBL10239769 | 0.87 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DRAPGEF3 | |
| SCHEMBL13300475 | 0.87 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DRAPGEF3 | |
| SCHEMBL13320207 | 0.87 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DRAPGEF3 | |
| SCHEMBL1106651 | 0.80 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DRAPGEF3 | |
| SCHEMBL10098847 | 0.80 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DRAPGEF3 | |
| SCHEMBL1130406 | 0.80 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DRAPGEF3 | |
| SCHEMBL13300471 | 0.80 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DRAPGEF3 | |
| SCHEMBL13300473 | 0.80 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DRAPGEF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304531-B2 | Process for the preparation of an (RP)-8-substituted cAMPS | SOLVELL AS (NO) | 2012-11-06 | — | — | US | disclosed |
| US-20100137237-A1 | PROCESS FOR THE PREPARATION OF AN (RP)-8-SUBSTITUTED CAMPS | LAURAS AS (NO) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137237-A1 | PROCESS FOR THE PREPARATION OF AN (RP)-8-SUBSTITUTED CAMPS | AMPD3, ATIC, PDE8A | PDE4A 31/4885PDE4B 53/4885PDE4C 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.