SCHEMBL133228

SCHEMBL133228

NCC(O)C1CCCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 1.00
KDM4E B2RXH2 2/20 0.95
GMNN O75496 1/20 0.95
LMNA P02545 1/20 0.95
MAPT P10636 1/20 0.95
BLM P54132 1/20 0.95
PMP22 Q01453 1/20 0.95
SMN1; SMN2 Q16637 1/20 0.95
EPHX1 P07099 2/20 0.56
ALDH1A1 P00352 1/20 0.47
SHBG P04278 1/20 0.39
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4078170 1.00 TP53 (1.00) TP53KDM4EGMNNLMNAMAPT
SCHEMBL23270700 1.00 TP53 (1.00) TP53KDM4EGMNNLMNAMAPT
SCHEMBL5228082 1.00 TP53 (1.00) TP53KDM4EGMNNLMNAMAPT
SCHEMBL4079339 1.00 TP53 (1.00) TP53KDM4EGMNNLMNAMAPT
Hydrochloric Acid SCHEMBL160732 0.97 KDM4E (1.00) TP53KDM4EGMNNLMNAMAPT
Hydrochloric Acid SCHEMBL2063394 0.97 KDM4E (1.00) TP53KDM4EGMNNLMNAMAPT
SCHEMBL3647508 0.97
SCHEMBL22535894 0.97
Hydrochloric Acid SCHEMBL19642704 0.95 KDM4E (0.95) TP53KDM4EGMNNLMNAMAPT
Hydrochloric Acid SCHEMBL30187467 0.95 KDM4E (0.95) TP53KDM4EGMNNLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 341 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116120554-A Composition for optical lens material with high refractive index and low thermal expansion coefficient 益丰新材料股份有限公司 2023-05-16 CN claimed
US-20210330606-A1 GLUCOSE CONSUMPTION ACCELERATOR AND GLYCOLYSIS ACCELERATOR SHINKO SANGYO CO., LTD. (JP) 2021-10-28 US claimed
EP-3639818-B1 GLUCOSE CONSUMPTION PROMOTER AND GLYCOLYSIS PROMOTER SHINKO SANGYO CO LTD (JP) 2021-07-07 EP claimed
CN-111093644-A Glucose consumption promoter and glycolysis promoter 株式会社亲广产业 2020-05-01 CN claimed
EP-3639818-A1 GLUCOSE CONSUMPTION PROMOTER AND GLYCOLYSIS PROMOTER Shinko Sangyo Co., Ltd. (JP) 2020-04-22 EP claimed
WO-2020026471-A1 GLUCOSE CONSUMPTION PROMOTER AND GLYCOLYSIS PROMOTER 株式会社親広産業 2020-02-06 WO claimed
WO-2020026570-A1 GLUCOSE CONSUMPTION PROMOTER AND GLYCOLYSIS PROMOTER 株式会社親広産業 2020-02-06 WO claimed
US-10109428-B2 Process to improve coverage and electrical performance of solid electrolytic capacitors KEMET ELECTRONICS CORPORATION (US) 2018-10-23 US claimed
US-20170338048-A1 Process to Improve Coverage and Electrical Performance of Solid Electrolytic Capacitors KEMET ELECTRONICS CORPORATION 2017-11-23 US claimed
US-9761347-B2 Process to improve coverage and electrical performance of solid electrolytic capacitor KEMET ELECTRONICS CORPORATION (US) 2017-09-12 US claimed
WO-2007101859-A1 SUBSTITUTED PYRAZOLOPYRIMIDINES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF FOR CONTROLLING PARASITIC FUNGI AND AGENTS CONTAINING THE LATTER BASF SE (DE) 2007-09-13 WO claimed
WO-2007101871-A1 SUBSTITUTED IMIDAZOLOPYRIMIDINES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF FOR CONTROLLING PARASITIC FUNGI AND AGENTS CONTAINING THE LATTER BASF SE (DE) 2007-09-13 WO claimed
EP-1501884-A1 AMINO-FUNCTIONAL POLYSILOXANES AND THEIR USE IN COATINGS SigmaKalon Services B.V. (NL) 2005-02-02 EP claimed
WO-2003093352-A1 AMINO-FUNCTIONAL POLYSILOXANES AND THEIR USE IN COATINGS SIGMAKALON SERVICES B.V. (NL) 2003-11-13 WO claimed
US-6316671-B1 DISSOLVING RACEMIC MIXTURE WITH ENANTIOMORPH OF N-TOSYL-LEUCINE IN PURE ALCOHOL; ISOLATING LESS SOLUBLE CRYSTALLIZED SALT UNIVERSITE DE ROUEN (FR) 2001-11-13 US claimed
EP-0946467-A1 METHOD FOR SPLITTING 1-AMINO-ALKAN-2-OL COMPOUNDS UNIVERSITE DE ROUEN (FR) 1999-10-06 EP claimed
WO-1998023559-A1 METHOD FOR SPLITTING 1-AMINO-ALKAN-2-OL COMPOUNDS UNIVERSITE DE ROUEN (FR) 1998-06-04 WO claimed
US-4759861-A Consists of an aliphatic mono- or di-carboxylic acid, a dimer or trimer of said dicarboxylic acid, petroleum sulfonic acid and naphthenic acid or salt NIPPON OIL CO., LTD. (JP) 1988-07-26 US claimed
US-4011311-A GELS, DEODORANTS, ADHESIVES AKZO N.V. (NL) 1977-03-08 US claimed
US-3968104-A SOLVENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210330606-A1 GLUCOSE CONSUMPTION ACCELERATOR AND GLYCOLYSIS ACCELERATOR SLC2A1, SLC2A2, SLC2A8 TP53 3344/4885KDM4E 646/4885GMNN 382/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.