SCHEMBL1332365

SCHEMBL1332365

NC(=O)CC[C@H](N[15NH2])C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.52
ALOX15 P16050 1/20 0.52
BLM P54132 1/20 0.52
PMP22 Q01453 1/20 0.52
GNPAT O15228 2/20 0.50
MMP2 P08253 2/20 0.45
MMP9 P14780 2/20 0.45
CA2 P00918 5/20 0.44
CA1 P00915 4/20 0.44
FOLH1 Q04609 4/20 0.43
RIMKLA Q8IXN7 1/20 0.43
NAALAD2 Q9Y3Q0 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.41
TGFBR1 P36897 1/20 0.38
GGH Q92820 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4760379 1.00 KMT2A (0.52) KMT2AALOX15BLMPMP22GNPAT
SCHEMBL4760380 1.00 KMT2A (0.52) KMT2AALOX15BLMPMP22GNPAT
SCHEMBL1332255 1.00 KMT2A (0.52) KMT2AALOX15BLMPMP22GNPAT
SCHEMBL21242720 0.89 GNPAT (0.63) KMT2AALOX15BLMPMP22GNPAT
SCHEMBL30466243 0.84 KMT2A (0.43) KMT2AALOX15BLMPMP22GNPAT
SCHEMBL18293383 0.84 KMT2A (0.43) KMT2AALOX15BLMPMP22GNPAT
SCHEMBL14625016 0.84 FOLH1 (0.61) KMT2ABLMGNPATFOLH1RIMKLA
SCHEMBL21518472 0.84 KMT2A (0.54) KMT2AALOX15BLMPMP22MMP2
SCHEMBL538658 0.84 FOLH1 (0.61) KMT2ABLMGNPATFOLH1RIMKLA
SCHEMBL4528455 0.84 FOLH1 (0.61) KMT2ABLMGNPATFOLH1RIMKLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9673030-B2 Computer readable storage mediums, methods and systems for normalizing chemical profiles in biological or medical samples detected by mass spectrometry EMORY UNIVERSITY (US) 2017-06-06 US disclosed
US-20110282587-A1 COMPUTER READABLE STORAGE MEDIUMS, METHODS AND SYSTEMS FOR NORMALIZING CHEMICAL PROFILES IN BIOLOGICAL OR MEDICAL SAMPLES DETECTED BY MASS SPECTROMETRY EMORY UNIVERSITY (US) 2011-11-17 US disclosed