Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.61 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.61 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.61 |
| ▸ | GNPAT | O15228 | 2/20 | 0.61 |
| ▸ | GGH | Q92820 | 1/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4528455 | 1.00 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| SCHEMBL14625016 | 1.00 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| SCHEMBL27608194 | 0.98 | GNPAT (0.59) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| Formic Acid SCHEMBL30874324 | 0.92 | GNPAT (0.54) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| SCHEMBL13465054 | 0.84 | FOLH1 (0.48) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| SCHEMBL4760379 | 0.84 | KMT2A (0.52) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| SCHEMBL18467856 | 0.84 | FOLH1 (0.48) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| SCHEMBL1332365 | 0.84 | KMT2A (0.52) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| SCHEMBL1332255 | 0.84 | KMT2A (0.52) | FOLH1NAALAD2RIMKLAGNPATGGH | |
| SCHEMBL4760380 | 0.84 | KMT2A (0.52) | FOLH1NAALAD2RIMKLAGNPATGGH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024198046-A1 | BIOMARKER AND SYSTEM FOR PREDICTING EVOLUTION INTO ACLF OR DEATH OF ACLF PATIENT, AND USES THEREOF | 上海甘宁医疗科技有限公司 | 2024-10-03 | — | — | WO | claimed |
| US-20200270202-A1 | POTENT INHIBITORS OF ASPARTATE N-ACETYL-TRANSFERASE FOR THE TREATMENT OF CANAVAN DISEASE | THE UNIVERSITY OF TOLEDO (US) | 2020-08-27 | — | — | US | claimed |
| WO-2017172476-A1 | POTENT INHIBITORS OF ASPARTATE N-ACETYL-TRANSFERASE FOR THE TREATMENT OF CANAVAN DISEASE | THE UNIVERSITY OF TOLEDO (US) | 2017-10-05 | — | — | WO | claimed |
| CN-104090095-A | Molecular conjugate | VENTANA MED SYST INC | 2014-10-08 | — | — | CN | claimed |
| CN-101029131-A | Branching poly-ethylene and its production | NAT DEFENCE SCIENCE & TECHNOLO (CN) | 2007-09-05 | — | — | CN | claimed |
| US-20060058221-A1 | Baclofen conjugate and a pharmaceutical composition for treatment of neuronal disorders | MILLER LANDON C | 2006-03-16 | — | — | US | claimed |
| WO-2024198046-A1 | BIOMARKER AND SYSTEM FOR PREDICTING EVOLUTION INTO ACLF OR DEATH OF ACLF PATIENT, AND USES THEREOF | 上海甘宁医疗科技有限公司 | 2024-10-03 | — | — | WO | disclosed |
| US-20240116984-A1 | MODIFIED PEPTIDES FOR THE INHIBITION OF ABNORMAL TAU ACCUMULATION | NATIONAL SCIENCE FOUNDATION | 2024-04-11 | — | — | US | disclosed |
| EP-4329791-A1 | MODIFIED PEPTIDES FOR THE INHIBITION OF ABNORMAL TAU ACCUMULATION | University of Notre Dame du Lac (US) | 2024-03-06 | — | — | EP | disclosed |
| CN-117510828-A | Tri-arm polyethylene glycol derivative containing amino acid residue | 厦门赛诺邦格生物科技股份有限公司 | 2024-02-06 | — | — | CN | disclosed |
| EP-4171237-A1 | USE OF AN ORGANO-MINERAL COMPOSITION VIA FOLIAR APPLICATION TO STIMULATE PLANT DEVELOPMENT IN THE PRESENCE OF AT LEAST ONE ABIOTIC STRESS OR BIOTIC STRESS | Olmix (FR) | 2023-05-03 | — | — | EP | disclosed |
| CN-111182911-B | Composition for protecting retinal nerve cells comprising processed product of cowberry fruit and processed product of pine bark | 参天制药株式会社 | 2023-04-04 | — | — | CN | disclosed |
| CN-110234635-B | Novel substituted benzimidazole derivatives as D-amino oxidase (DAAO) inhibitors | 宇凤·简·曾 | 2023-03-10 | — | — | CN | disclosed |
| CN-1611524-A | Polyethylene glycol amino acid N-internal ring carbonyl anhydride active derivatives, and medicinal bonding compound and gel thereof | JIANKAI SCI & TECH CO LTD BEIJ (CN) | 2005-05-04 | — | — | CN | disclosed |
| WO-2004058804-A1 | PEPTIDES AND THERAPEUTIC USES THEREOF | WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2004-07-15 | — | — | WO | disclosed |
| CN-1476325-A | Delivery system for active substances and method for protecting and administering active substances | 新河药品股份有限公司 | 2004-02-18 | — | — | CN | disclosed |
| WO-1997015676-A2 | CANDIDA TOPOISOMERASEIGENE | ABBOTT LABORATORIES (US) | 1997-05-01 | — | — | WO | disclosed |
| CN-1030353-C | Nonlinear optical materials | DU PONT (US) | 1995-11-22 | — | — | CN | disclosed |
| CN-1059344-A | Nonlinear optical material | DU PONT (US) | 1992-03-11 | — | — | CN | disclosed |
| US-4515891-A | ENZYMATIC HYDROLYSIS OF CELL WALLS OF LACTOBACILLUS OR CORYNEBACTERIUM | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1985-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116984-A1 | MODIFIED PEPTIDES FOR THE INHIBITION OF ABNORMAL TAU ACCUMULATION | PRNP, MAPT, APP | FOLH1 4299/4885NAALAD2 381/4885RIMKLA 81/4885 |
| US-20200270202-A1 | POTENT INHIBITORS OF ASPARTATE N-ACETYL-TRANSFERASE FOR THE TREATMENT OF CANAVAN DISEASE | GOT1, ACAT1, GOT2 | FOLH1 281/4885NAALAD2 9/4885RIMKLA 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.