Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14175336 | 0.87 | TSHR (0.60) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL21272 | 0.87 | TSHR (1.00) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL13974192 | 0.87 | TSHR (1.00) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL17549552 | 0.87 | TSHR (1.00) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL2786172 | 0.84 | TSHR (0.95) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL20543294 | 0.84 | TSHR (0.95) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL23668239 | 0.84 | TSHR (0.95) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL15215 | 0.84 | TSHR (0.95) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL21834095 | 0.84 | TSHR (0.95) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL19410576 | 0.84 | TSHR (0.95) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718746-B2 | Anion-binding polymers and uses thereof | ILYPSA, INC. (US) | 2010-05-18 | — | — | US | disclosed |
| US-7718746-B2 | Anion-binding polymers and uses thereof | ILYPSA, INC. (US) | 2010-05-18 | — | — | US | disclosed |