Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8146040 | 0.84 | ALDH1A1 (0.56) | ALDH1A1PDE10ACASP1DHFRMEN1 | |
| SCHEMBL648323 | 0.83 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AGAACYP3A4 | |
| SCHEMBL99566 | 0.82 | ALDH1A1 (0.54) | ALDH1A1PDE10ACASP1DHFRMEN1 | |
| SCHEMBL21295902 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MEN1MAPTKMT2AGAA | |
| Methane SCHEMBL28805939 | 0.81 | ALDH1A1 (0.52) | ALDH1A1PDE10ACASP1DHFRMEN1 | |
| SCHEMBL8953996 | 0.81 | ALDH1A1 (0.52) | ALDH1A1PDE10ACASP1DHFRMEN1 | |
| Hydrochloric Acid SCHEMBL10585120 | 0.81 | ALDH1A1 (0.52) | ALDH1A1PDE10ACASP1DHFRMEN1 | |
| Hydrochloric Acid SCHEMBL7543824 | 0.81 | ALDH1A1 (0.52) | ALDH1A1PDE10ACASP1DHFRMEN1 | |
| SCHEMBL1697580 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL1696301 | 0.79 | ALDH1A1 (0.50) | ALDH1A1PDE10ACASP1DHFRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065515-A1 | ELECTRON-TRANSPORTING POLYMERS | GENERAL ELECTRIC COMPANY (US) | 2010-06-10 | — | — | WO | disclosed |