⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133286 | 1.00 | — | — | |
| SCHEMBL27324011 | 0.77 | — | — | |
| Ethylene Glycol SCHEMBL14742401 | 0.75 | PTGS1 (0.41) | — | |
| SCHEMBL8731583 | 0.74 | — | — | |
| SCHEMBL22728604 | 0.74 | LDHA (0.42) | — | |
| SCHEMBL7208264 | 0.74 | — | — | |
| SCHEMBL14893046 | 0.74 | — | — | |
| SCHEMBL209221 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL5422913 | 0.72 | LDHA (0.40) | — | |
| SCHEMBL28219859 | 0.72 | LDHA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749031-B1 | USE OF A scFv FOR DIMINISHING AN EXISTING BIOFILM | HAPTOGEN LTD (GB) | 2013-07-17 | — | — | EP | disclosed |
| US-20130045208-A1 | Methods for the Treatment of an Infectious Bacterial Disease with an Anti-Lactone or Lactone Derived Signal Molecules Antibody | Haptogen, Ltd. (GB) | 2013-02-21 | — | — | US | disclosed |
| US-20130011400-A1 | Methods For Inducing Autolysis In Infectious Bacteria | HAPTOGEN LTD. (GB) | 2013-01-10 | — | — | US | disclosed |
| US-8168397-B2 | Methods for the treatment of an infectious bacterial disease with an anti-lactone or lactone derived signal molecules antibody | HAPTOGEN LTD. (GB) | 2012-05-01 | — | — | US | disclosed |
| EP-1528935-B1 | METHODS FOR THE TREATMENT OF AN INFECTIOUS BACTERIAL DISEASE WITH AN ANTI-LACTONE OR LACTONE DERIVED SIGNAL MOLECULES ANTIBODY | HAPTOGEN LTD (GB) | 2012-03-21 | — | — | EP | disclosed |
| EP-1730197-B1 | METHODS FOR INDUCING AUTOLYSIS IN INFECTIOUS BACTERIA | HAPTOGEN LTD (GB) | 2012-03-07 | — | — | EP | disclosed |
| EP-2281839-A2 | Methods for reducing biofilm formation in infectious bacteria | Haptogen Ltd (GB) | 2011-02-09 | — | — | EP | disclosed |
| US-20110027280-A1 | Methods For Inducing Autolysis In Infectious Bacteria | HAPTOGEN LTD. (GB) | 2011-02-03 | — | — | US | disclosed |
| EP-2261260-A2 | Methods for inducing autolysis in infectious bacteria | Haptogen Ltd (GB) | 2010-12-15 | — | — | EP | disclosed |
| EP-2260868-A2 | Methods for the treatment of an infectious bacterial disease with anti-lactone or lactone derived signal molecules antibody | Haptogen Ltd (GB) | 2010-12-15 | — | — | EP | disclosed |
| US-20090117109-A1 | Methods For Reducing Biofilm Formation In Infectious Bacteria | HAPTOGEN LTD. (GB) | 2009-05-07 | — | — | US | disclosed |
| US-20070218058-A1 | Methods For Inducing Autolysis In Infectious Bacteria | HAPTOGEN LTD. POLWARTH BUILDING (GB) | 2007-09-20 | — | — | US | disclosed |
| EP-1749031-A2 | METHODS FOR REDUCING BIOFILM FORMATION IN INFECTIOUS BACTERIA | Haptogen Ltd (GB) | 2007-02-07 | — | — | EP | disclosed |
| EP-1730197-A2 | METHODS FOR INDUCING AUTOLYSIS IN INFECTIOUS BACTERIA | Haptogen Ltd (GB) | 2006-12-13 | — | — | EP | disclosed |
| US-20060165704-A1 | Methods for the treatment of an infectious bacterial disease with an anti-lactone or lactone derived signal molecules antibody | HAPTOGEN LTD. (GB) | 2006-07-27 | — | — | US | disclosed |
| WO-2005111080-A2 | METHODS FOR REDUCING BIOFILM FORMATION IN INFECTIOUS BACTERIA | HAPTOGEN LTD (GB) | 2005-11-24 | — | — | WO | disclosed |
| WO-2005094883-A2 | METHODS FOR INDUCING AUTOLYSIS IN INFECTIOUS BACTERIA | HAPTOGEN LTD (GB) | 2005-10-13 | — | — | WO | disclosed |
| CN-1681531-A | Methods of treating infectious bacterial diseases with antibodies against lactones or lactone-derived signal molecules | HAPTOGEN LTD (GB) | 2005-10-12 | — | — | CN | disclosed |
| EP-1528935-A1 | METHODS FOR THE TREATMENT OF AN INFECTIOUS BACTERIAL DISEASE WITH AN ANTI-LACTONE OR LACTONE DERIVED SIGNAL MOLECULES ANTIBODY | Haptogen Ltd (GB) | 2005-05-11 | — | — | EP | disclosed |
| WO-2004014423-A1 | METHODS FOR THE TREATMENT OF AN INFECTIOUS BACTERIAL DISEASE WITH AN ANTI-LACTONE OR LACTONE DERIVED SIGNAL MOLECULES ANTIBODY | HAPTOGEN LTD (GB) | 2004-02-19 | — | — | WO | disclosed |