Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.77 |
| ▸ | CA1 | P00915 | 5/20 | 0.68 |
| ▸ | CA12 | O43570 | 1/20 | 0.68 |
| ▸ | CA3 | P07451 | 1/20 | 0.68 |
| ▸ | AR | P10275 | 1/20 | 0.68 |
| ▸ | CA4 | P22748 | 1/20 | 0.68 |
| ▸ | CA6 | P23280 | 1/20 | 0.68 |
| ▸ | CA5A | P35218 | 1/20 | 0.68 |
| ▸ | CA7 | P43166 | 1/20 | 0.68 |
| ▸ | CA9 | Q16790 | 1/20 | 0.68 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.68 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13579142 | 1.00 | CA2 (0.77) | CA2CA1CA12CA3AR | |
| N-Desethyl Dorzolamide SCHEMBL10576632 | 0.87 | CA2 (1.00) | CA2CA1CA12CA3AR | |
| N-Desethyl Dorzolamide SCHEMBL16654313 | 0.86 | CA2 (0.97) | CA2CA1CA12CA3AR | |
| SCHEMBL2348864 | 0.86 | CA2 (0.73) | CA2CA1CA12CA3AR | |
| SCHEMBL15545115 | 0.86 | CA2 (0.73) | CA2CA1CA12CA3AR | |
| SCHEMBL15604778 | 0.86 | CA2 (0.73) | CA2CA1CA12CA3AR | |
| SCHEMBL19929801 | 0.86 | CA2 (0.73) | CA2CA1CA12CA3AR | |
| SCHEMBL678160 | 0.83 | CA2 (1.00) | CA2CA1CA12CA3AR | |
| SCHEMBL22372488 | 0.83 | CA2 (1.00) | CA2CA1CA12CA3AR | |
| SCHEMBL9525726 | 0.83 | CA2 (1.00) | CA2CA1CA12CA3AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010061398-A1 | PROCESS FOR PREPARING DORZOLAMIDE HYDROCHLORIDE AND ITS INTERMEDIATE | SUVEN LIFE SCIENCES LIMITED (IN) | 2010-06-03 | — | — | WO | disclosed |