SCHEMBL133307

SCHEMBL133307

CC(C)(C)OC(=O)N[C@H]1CCNC1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BTK Q06187 1/20 0.50
EPHX2 P34913 1/20 0.47
CTSK P43235 2/20 0.47
GAA P10253 2/20 0.45
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
EPHX1 P07099 2/20 0.41
KDM1A O60341 1/20 0.41
MAOB P27338 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
REN P00797 1/20 0.40
CYP2C9 P11712 1/20 0.39
HSD11B1 P28845 1/20 0.39
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KCNH2 Q12809 1/20 0.39
KCNA3 P22001 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48274 1.00 BTK (0.50) BTKEPHX2CTSKGAACA1
SCHEMBL183834 1.00 BTK (0.50) BTKEPHX2CTSKGAACA1
SCHEMBL25306007 1.00 BTK (0.50) BTKEPHX2CTSKGAACA1
SCHEMBL25306009 1.00 BTK (0.50) BTKEPHX2CTSKGAACA1
Hydrochloric Acid SCHEMBL30563288 0.98 BTK (0.49) BTKEPHX2CTSKGAACA1
Hydrochloric Acid SCHEMBL27995727 0.98 BTK (0.49) BTKEPHX2CTSKGAACA1
Hydrochloric Acid SCHEMBL31088698 0.98 BTK (0.49) BTKEPHX2CTSKGAACA1
Bicarbonate SCHEMBL48015 0.97 BTK (0.51) BTKEPHX2CTSKGAACA1
SCHEMBL1412188 0.92 EPHX1 (0.51) BTKEPHX2CTSKGAACA1
SCHEMBL8960563 0.92 EPHX1 (0.51) BTKEPHX2CTSKGAACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2225 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146205-A Targeting PD-L1 micromolecular PET probe and preparation method and application thereof 华中科技大学同济医学院附属同济医院 2024-06-07 CN claimed
CN-115160310-B Alternanthene derivatives as CDK2/Topo I inhibitors, preparation method thereof and antitumor application thereof 中国人民解放军北部战区总医院 2023-06-23 CN claimed
CN-115160298-B Tacrine-sulfonamide derivative and preparation method and application thereof 中国人民解放军北部战区总医院 2023-05-23 CN claimed
CN-115160310-A Sinomenine derivatives as CDK2/Topo I inhibitor, and preparation method and anti-tumor application thereof 中国人民解放军北部战区总医院 2022-10-11 CN claimed
CN-115160298-A Tacrine-sulfonamide derivative and preparation method and application thereof 中国人民解放军北部战区总医院 2022-10-11 CN claimed
CN-115124511-A Tacrine derivative, preparation method thereof and application of tacrine derivative as CDK2/9 inhibitor 中国人民解放军北部战区总医院 2022-09-30 CN claimed
CN-210620479-U Waste water treatment device for producing derivatives of (2S,4S) -4-tert-butyloxycarbonylaminopyrrolidine 南京道尔顿化学技术有限公司 2020-05-26 CN claimed
CN-102477009-B Substitutive (S)-benaldehyde sulfonyl pyrrolidine-3-amino derivative, and preparation method and application thereof UNIV TSINGHUA GRADUATE SCHOOL 2014-01-01 CN claimed
CN-102477009-A Substitutive (S)-benaldehyde sulfonyl pyrrolidine-3-amino derivative, and preparation method and application thereof UNIV TSINGHUA GRADUATE SCHOOL 2012-05-30 CN claimed
EP-1601354-A4 OXADIAZOLINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX INTREXON CORP (US) 2009-08-12 EP claimed
EP-1601354-A2 OXADIAZOLINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX RheoGene Holdings Inc. (US) 2005-12-07 EP claimed
WO-2005017126-A2 OXADIAZOLINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX RHEOGENE HOLDINGS, INC. (US) 2005-02-24 WO claimed
WO-2026106389-A1 NMT INHIBITOR AND USE THEREOF 주식회사 이노보테라퓨틱스 2026-05-21 WO disclosed
US-12630511-B2 Benzamide derivative, preparation method therefor, and pharmaceutical composition comprising same as active ingredient for prevention or treatment of cancer KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-05-19 US disclosed
CN-122036690-A Heteroaromatic ring compound, pharmaceutical composition and application thereof 马应龙药业集团股份有限公司 2026-05-15 CN disclosed
CN-122010912-A Antiviral 1, 3-dioxoindene compounds 诺华股份有限公司 2026-05-12 CN disclosed
EP-0391169-A2 Enantiomeric pure 7-(3-amino-1-pyrrolidinyl)-chinolon-and-naphthyridon carboxylic acids BAYER AG (DE) 1990-10-10 EP disclosed
US-4916141-A ANTIBACTERIAL WARNER-LAMBERT COMPANY (US) 1990-04-10 US disclosed
US-4851418-A Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent WARNER-LAMBERT COMPANY (US) 1989-07-25 US disclosed
EP-0304087-A2 Quinolone and naphthyridine antibacterial agents containing an alpha-amino acid in the side chain of the 7-substituent WARNER-LAMBERT COMPANY (US) 1989-02-22 EP disclosed