SCHEMBL48274

SCHEMBL48274

CC(C)(C)OC(=O)NC1CCNC1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BTK Q06187 1/20 0.50
EPHX2 P34913 1/20 0.47
CTSK P43235 2/20 0.47
GAA P10253 2/20 0.45
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
EPHX1 P07099 2/20 0.41
KDM1A O60341 1/20 0.41
MAOB P27338 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
REN P00797 1/20 0.40
CYP2C9 P11712 1/20 0.39
HSD11B1 P28845 1/20 0.39
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KCNH2 Q12809 1/20 0.39
KCNA3 P22001 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL183834 1.00 BTK (0.50) BTKEPHX2CTSKGAACA1
SCHEMBL25306007 1.00 BTK (0.50) BTKEPHX2CTSKGAACA1
SCHEMBL133307 1.00 BTK (0.50) BTKEPHX2CTSKGAACA1
SCHEMBL25306009 1.00 BTK (0.50) BTKEPHX2CTSKGAACA1
Hydrochloric Acid SCHEMBL30563288 0.98 BTK (0.49) BTKEPHX2CTSKGAACA1
Hydrochloric Acid SCHEMBL27995727 0.98 BTK (0.49) BTKEPHX2CTSKGAACA1
Hydrochloric Acid SCHEMBL31088698 0.98 BTK (0.49) BTKEPHX2CTSKGAACA1
Bicarbonate SCHEMBL48015 0.97 BTK (0.51) BTKEPHX2CTSKGAACA1
SCHEMBL1412188 0.92 EPHX1 (0.51) BTKEPHX2CTSKGAACA1
SCHEMBL8960563 0.92 EPHX1 (0.51) BTKEPHX2CTSKGAACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3402 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119023611-A Real-time monitoring method for ketone-amine conversion reaction process and application thereof 北京衍微科技有限公司 2024-11-26 CN claimed
CN-115160310-B Alternanthene derivatives as CDK2/Topo I inhibitors, preparation method thereof and antitumor application thereof 中国人民解放军北部战区总医院 2023-06-23 CN claimed
CN-115160310-A Sinomenine derivatives as CDK2/Topo I inhibitor, and preparation method and anti-tumor application thereof 中国人民解放军北部战区总医院 2022-10-11 CN claimed
CN-114989165-A Compound or composition for resisting retention bacteria and biofilm bacteria and application thereof 青岛大学附属医院 2022-09-02 CN claimed
CN-102245599-B Novel 4-amino-4-oxobutanoyl peptides as inhibitors of viral replication ACHILLION PHARMACEUTICALS INC 2014-05-14 CN claimed
CN-103402997-A Diaminopyrimidine derivatives and process for preparing same YUHAN INC 2013-11-20 CN claimed
WO-2013130660-A1 AMIDES AS PIM INHIBITORS AMGEN INC. (US) 2013-09-06 WO claimed
EP-0828754-B1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER (US) 2005-02-02 EP claimed
EP-0391169-A2 Enantiomeric pure 7-(3-amino-1-pyrrolidinyl)-chinolon-and-naphthyridon carboxylic acids BAYER AG (DE) 1990-10-10 EP claimed
JP-8259531-A None JP disclosed
US-20260146042-A1 PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USES NOVARTIS AG (CH) 2026-05-28 US disclosed
EP-3802500-B1 MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF CRINETICS PHARMACEUTICALS INC (US) 2026-05-27 EP disclosed
EP-4747243-A1 LIGANDS AND COMPOSITIONS AND METHODS OF USE THEREOF Baylor College of Medicine (US) 2026-05-27 EP disclosed
EP-4747260-A1 MACROCYCLES FOR THE TREATMENT OF AUTOIMMUNE DISEASE F. Hoffmann-La Roche AG (CH) 2026-05-27 EP disclosed
US-4550103-A Antibacterial 1-oxo-benzoquinolizine-2-carboxylic acids WARNER-LAMBERT COMPANY (US) 1985-10-29 US disclosed
US-4550104-A Antibacterial thiazolo-quinolines and thiazolo-naphthyridines WARNER-LAMBERT COMPANY (US) 1985-10-29 US disclosed
US-4539401-A Pyridobenzoxazine derivatives useful as antibacterial agents DAIICHI SEIYAKU CO., LTD. (JP) 1985-09-03 US disclosed
EP-0153163-A2 7-Substituted-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids; 7-substituted-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acids; their derivatives; and a process for preparing the compounds WARNER-LAMBERT COMPANY (US) 1985-08-28 EP disclosed
US-4535161-A ANTIBIOTIC, BACTERICIDE DAIICHI SEIYAKU CO., LTD. (JP) 1985-08-13 US disclosed
EP-0101829-A2 Tricyclic compounds, a process for their production and pharmaceutical compositions containing said compounds DAIICHI SEIYAKU CO., LTD. (JP) 1984-03-07 EP disclosed