Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.37 |
| ▸ | AR | P10275 | 3/20 | 0.37 |
| ▸ | DPP4 | P27487 | 5/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3339689 | 0.91 | DPP4 (0.40) | PGRNR3C1NR3C2ARDPP4 | |
| SCHEMBL3342927 | 0.84 | DPP4 (0.39) | PGRNR3C1NR3C2ARDPP4 | |
| SCHEMBL3341183 | 0.79 | DPP4 (0.41) | DPP4DPP7CYP17A1GAAHPGD | |
| SCHEMBL3339938 | 0.76 | DPP4 (0.45) | DPP4DPP7GAAHPGDMAPK1 | |
| SCHEMBL3339591 | 0.75 | NPC1 (0.45) | PGRDPP4DPP7EPHX2NR1H4 | |
| SCHEMBL3340510 | 0.75 | NPC1 (0.43) | DPP4DPP7CYP17A1EPHX2NR1H4 | |
| SCHEMBL3339344 | 0.73 | DPP4 (0.41) | DPP4DPP7CYP17A1GAAHPGD | |
| SCHEMBL3340793 | 0.70 | NPC1 (0.50) | MAPK1S1PR1 | |
| SCHEMBL3339352 | 0.70 | DPP4 (0.38) | DPP4DPP7S1PR1 | |
| SCHEMBL13330765 | 0.69 | NPC1 (0.40) | DPP4DPP7CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065760-A1 | IMIDAZO [1,2A] PYRIDINE DERIVATIVES, THEIR USE AS S1P1 AGONISTS AND METHODS FOR THEIR PRODUCTION | EXELIXIS, INC. (US) | 2010-06-10 | — | — | WO | disclosed |