Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.41 |
| ▸ | HAVCR2 | Q8TDQ0 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | SLC2A2 | P11168 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3339344 | 0.92 | DPP4 (0.41) | DPP4DPP7HAVCR2HPGDMAPK1 | |
| SCHEMBL3339938 | 0.87 | DPP4 (0.45) | DPP4DPP7HAVCR2HPGDMAPK1 | |
| SCHEMBL3339689 | 0.87 | DPP4 (0.40) | DPP4DPP7HAVCR2HPGDMAPK1 | |
| SCHEMBL3340510 | 0.82 | NPC1 (0.43) | DPP4DPP7HAVCR2CYP17A1NPC1 | |
| SCHEMBL3342927 | 0.81 | DPP4 (0.39) | DPP4DPP7HAVCR2HPGDMAPK1 | |
| SCHEMBL3339591 | 0.80 | NPC1 (0.45) | DPP4DPP7HAVCR2NPC1RAB9A | |
| SCHEMBL13330780 | 0.80 | NPC1 (0.39) | HPGDMAPK1NPC1RAB9ATP53 | |
| SCHEMBL13330734 | 0.79 | PGR (0.37) | DPP4DPP7HPGDMAPK1GAA | |
| SCHEMBL3340876 | 0.76 | NPC1 (0.42) | DPP4DPP7NPC1RAB9ATDP1 | |
| SCHEMBL3340793 | 0.76 | NPC1 (0.50) | MAPK1NPC1RAB9ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160369-A1 | S1P1 Agonists and Methods of Making And Using | EXELIXIS, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100160369-A1 | S1P1 Agonists and Methods of Making And Using | EXELIXIS, INC. (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160369-A1 | S1P1 Agonists and Methods of Making And Using | S1PR1, S1PR5, S1PR3 | DPP4 2190/4885DPP7 1882/4885HAVCR2 1390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.