Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14475236 | 0.83 | GAA (0.46) | GAAALDH1A1CD44KDM1ACA1 | |
| SCHEMBL8492289 | 0.82 | GAA (0.50) | GAAALDH1A1CD44KDM1ACA1 | |
| SCHEMBL29659108 | 0.82 | GAA (0.50) | GAAALDH1A1CD44KDM1ACA1 | |
| SCHEMBL30573328 | 0.79 | GAA (0.53) | GAAALDH1A1CD44KDM1ACA1 | |
| SCHEMBL1477638 | 0.79 | GAA (0.53) | GAAALDH1A1CD44KDM1ACA1 | |
| SCHEMBL19657881 | 0.79 | GAA (0.53) | GAAALDH1A1CD44CA1CA2 | |
| SCHEMBL14578394 | 0.79 | GAA (0.53) | GAAALDH1A1CD44KDM1ACA1 | |
| SCHEMBL29939627 | 0.77 | KDM1A (0.43) | GAAALDH1A1CD44KDM1ACA1 | |
| SCHEMBL1397082 | 0.77 | KDM1A (0.43) | GAAALDH1A1CD44KDM1ACA1 | |
| SCHEMBL22824195 | 0.77 | ALDH1A1 (0.40) | ALDH1A1CA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065760-A1 | IMIDAZO [1,2A] PYRIDINE DERIVATIVES, THEIR USE AS S1P1 AGONISTS AND METHODS FOR THEIR PRODUCTION | EXELIXIS, INC. (US) | 2010-06-10 | — | — | WO | disclosed |