Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22912360 | 0.97 | CYP2C19 (0.46) | CYP2C19LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL26613581 | 0.91 | CYP2C19 (0.42) | CYP2C19LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL26613582 | 0.89 | CYP2C19 (0.41) | CYP2C19LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL17381511 | 0.86 | CYP2C19 (0.44) | CYP2C19LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22912362 | 0.86 | CYP2C19 (0.44) | CYP2C19LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL17381367 | 0.86 | CYP2C19 (0.49) | CYP2C19LMNAALDH1A1HPGDSMN1; SMN2 | |
| Cpi 613 SCHEMBL1062218 | 0.85 | CYP2C19 (0.59) | CYP2C19LMNAALDH1A1HPGDSMN1; SMN2 | |
| Cpi 613 SCHEMBL13333201 | 0.85 | CYP2C19 (0.59) | CYP2C19LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22299026 | 0.85 | CYP2C19 (0.48) | CYP2C19LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL17381514 | 0.84 | CYP2C19 (0.58) | CYP2C19LMNAALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010062381-A1 | ORGANELLE-SPECIFIC DRUG DELIVERY | SHORR ROBERT (US) | 2010-06-03 | — | — | WO | disclosed |