Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.44 |
| ▸ | CHRNA6 | Q15825 | 2/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27209196 | 0.72 | CHRNB2 (0.55) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL9715915 | 0.71 | GAA (0.50) | L3MBTL1GAAALDH1A1 | |
| SCHEMBL697858 | 0.71 | GAA (0.50) | L3MBTL1GAAALDH1A1 | |
| SCHEMBL13225976 | 0.71 | GAA (0.50) | L3MBTL1GAAALDH1A1 | |
| SCHEMBL4397787 | 0.71 | GAA (0.50) | L3MBTL1GAAALDH1A1 | |
| SCHEMBL30233086 | 0.70 | HRH3 (0.59) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL13225974 | 0.70 | GAA (0.48) | L3MBTL1GAAALDH1A1 | |
| SCHEMBL13225973 | 0.70 | GAA (0.48) | L3MBTL1GAAALDH1A1 | |
| SCHEMBL1933219 | 0.70 | GAA (0.48) | L3MBTL1GAAALDH1A1 | |
| SCHEMBL937482 | 0.70 | CHRNB2 (0.55) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009158698-A9 | TARGETED DELIVERY OF IMAGING PROBES FOR IN VIVO CELLULAR IMAGING | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2010-06-17 | — | — | WO | disclosed |
| WO-2009158698-A2 | TARGETED DELIVERY OF IMAGING PROBES FOR IN VIVO CELLULAR IMAGING | UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE (US) | 2009-12-30 | — | — | WO | disclosed |