Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | OGA | O60502 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13333373 | 0.92 | KDM4E (0.47) | TNIKKDM4EKDRTP53MAPT | |
| SCHEMBL3396815 | 0.86 | TNIK (0.61) | TNIKALDH1A1KDM4EKMT2AKDR | |
| SCHEMBL15712779 | 0.85 | TNIK (0.51) | TNIKTP53MAPT | |
| SCHEMBL15713027 | 0.79 | TNIK (0.55) | TNIKKMT2ATP53MAPT | |
| SCHEMBL3392252 | 0.79 | TNIK (0.60) | TNIKKDM4EKDRTP53MAPT | |
| SCHEMBL3394890 | 0.78 | TNIK (0.59) | TNIKKDM4EKDR | |
| SCHEMBL3398691 | 0.78 | TNIK (0.64) | TNIKGAA | |
| SCHEMBL3394602 | 0.78 | TNIK (0.60) | TNIKALDH1A1KDM4EKDRGAA | |
| SCHEMBL13333376 | 0.78 | TNIK (0.48) | TNIKTP53MAPT | |
| SCHEMBL3390733 | 0.78 | TNIK (0.62) | TNIKKDRIKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010064111-A1 | TNIK INHIBITOR AND THE USE | YAMADA TESSHI (JP) | 2010-06-10 | — | — | WO | disclosed |