Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 17/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13333406 | 0.88 | TNIK (0.50) | TNIKTP53MAPT | |
| SCHEMBL3397183 | 0.85 | TNIK (0.60) | TNIKTP53MAPT | |
| SCHEMBL13333373 | 0.83 | KDM4E (0.47) | TNIKTP53MAPT | |
| SCHEMBL13333153 | 0.83 | MAPT (0.51) | TNIKTP53MAPT | |
| SCHEMBL3396884 | 0.81 | TNIK (0.55) | TNIK | |
| SCHEMBL15713027 | 0.80 | TNIK (0.55) | TNIKTP53MAPT | |
| SCHEMBL13333401 | 0.80 | TNIK (0.52) | TNIKTP53MAPT | |
| SCHEMBL3394878 | 0.79 | TNIK (0.75) | TNIK | |
| SCHEMBL3394602 | 0.78 | TNIK (0.60) | TNIKMAPT | |
| SCHEMBL3392237 | 0.78 | TNIK (0.76) | TNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010064111-A1 | TNIK INHIBITOR AND THE USE | YAMADA TESSHI (JP) | 2010-06-10 | — | — | WO | disclosed |