Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 18/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.51 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394961 | 0.90 | TNIK (0.74) | TNIKLMNATP53POLBMAPT | |
| SCHEMBL3390775 | 0.88 | TNIK (0.75) | TNIKLMNATP53POLBMAPT | |
| SCHEMBL3396325 | 0.88 | TNIK (0.60) | TNIKLMNATP53POLBMAPT | |
| SCHEMBL3390831 | 0.84 | TNIK (0.64) | TNIKLMNATP53POLBMAPT | |
| SCHEMBL3397644 | 0.83 | TNIK (0.77) | TNIKIKBKETBK1 | |
| SCHEMBL3396744 | 0.83 | TBK1 (0.69) | TNIKLMNATP53POLBMAPT | |
| SCHEMBL3398216 | 0.82 | TNIK (0.59) | TNIKLMNATP53POLBMAPT | |
| SCHEMBL3398694 | 0.82 | TNIK (0.67) | TNIKLMNATP53POLBMAPT | |
| SCHEMBL3392675 | 0.82 | TNIK (0.71) | TNIKLMNATP53POLBMAPT | |
| SCHEMBL2367268 | 0.81 | TNIK (0.68) | TNIKLMNATP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010064111-A1 | TNIK INHIBITOR AND THE USE | YAMADA TESSHI (JP) | 2010-06-10 | — | — | WO | disclosed |