Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 17/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3396750 | 0.85 | TNIK (0.57) | TNIKMAPT | |
| SCHEMBL13333379 | 0.78 | TNIK (0.58) | TNIKMAPT | |
| SCHEMBL3396325 | 0.75 | TNIK (0.60) | TNIKMAPT | |
| SCHEMBL13333124 | 0.75 | TNIK (0.53) | TNIKMAPT | |
| SCHEMBL13333227 | 0.75 | TNIK (0.53) | TNIK | |
| SCHEMBL3393595 | 0.74 | TNIK (0.72) | TNIKMAPT | |
| SCHEMBL16710221 | 0.72 | TNIK (0.77) | TNIK | |
| SCHEMBL13333228 | 0.71 | TNIK (0.46) | TNIKMAPT | |
| SCHEMBL3397542 | 0.71 | TNIK (0.73) | TNIKMAPT | |
| SCHEMBL3393673 | 0.71 | TNIK (0.67) | TNIKMAPTCDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010064111-A1 | TNIK INHIBITOR AND THE USE | YAMADA TESSHI (JP) | 2010-06-10 | — | — | WO | disclosed |