Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 15/20 | 0.58 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.44 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.41 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3397644 | 0.85 | TNIK (0.77) | TNIKTBK1IKBKE | |
| SCHEMBL13333401 | 0.85 | TNIK (0.52) | TNIKMAPT | |
| SCHEMBL13333383 | 0.78 | TNIK (0.43) | TNIKMAPT | |
| SCHEMBL13333373 | 0.77 | KDM4E (0.47) | TNIKMAPT | |
| SCHEMBL3397313 | 0.76 | TNIK (0.75) | TNIKTBK1 | |
| SCHEMBL13333228 | 0.76 | TNIK (0.46) | TNIKTBK1PIP5K1CIKBKEMAPT | |
| SCHEMBL13333382 | 0.75 | TBK1 (0.45) | TNIKTBK1PIP5K1CIKBKEMAPT | |
| SCHEMBL13333376 | 0.75 | TNIK (0.48) | TNIKMAPT | |
| SCHEMBL3392237 | 0.75 | TNIK (0.76) | TNIK | |
| SCHEMBL3394878 | 0.74 | TNIK (0.75) | TNIK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010064111-A1 | TNIK INHIBITOR AND THE USE | YAMADA TESSHI (JP) | 2010-06-10 | — | — | WO | disclosed |