Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.47 |
| ▸ | CHRNA10 | Q9GZZ6 | 4/20 | 0.47 |
| ▸ | CHRNA9 | Q9UGM1 | 4/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL16105114 | 0.87 | HTT (0.45) | FFAR1FFAR4CHRNA7CHRNA10CHRNA9 | |
| Bromide SCHEMBL16105159 | 0.84 | CHRNA7 (0.49) | FFAR1FFAR4CHRNA7CHRNA10CHRNA9 | |
| Bromide SCHEMBL16105104 | 0.83 | CHRNA7 (0.57) | FFAR1FFAR4CHRNA7CHRNA10CHRNA9 | |
| Bromide SCHEMBL16105152 | 0.80 | NPC1 (0.50) | FFAR1FFAR4CHRNA7CHRNA10CHRNA9 | |
| Bromide SCHEMBL16105160 | 0.80 | FFAR1 (0.46) | FFAR1FFAR4CHRNA7CHRNA10CHRNA9 | |
| SCHEMBL13334233 | 0.79 | CHRNA7 (0.67) | CHRNA7CHRNA10CHRNA9ACHEKCNH2 | |
| SCHEMBL9333577 | 0.78 | FFAR1 (0.59) | FFAR1FFAR4KCNH2HRH3TSHR | |
| Bromide SCHEMBL3313506 | 0.78 | CHRNA7 (0.68) | CHRNA7CHRNA10CHRNA9ACHECHRNB2 | |
| SCHEMBL9333457 | 0.77 | FFAR1 (0.66) | FFAR1FFAR4CHRM2ADRA2AADORA3 | |
| SCHEMBL8455035 | 0.76 | FFAR1 (0.49) | FFAR1FFAR4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846937-B2 | Mono quaternary ammonium salts and methods for modulating neuronal nicotinic acetylcholine receptors | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2014-09-30 | — | — | US | disclosed |
| US-20100113511-A1 | Mono Quaternary Ammonium Salts and Methods for Modulating Neuronal Nicotinic Acetylcholine Receptors | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113511-A1 | Mono Quaternary Ammonium Salts and Methods for Modulating Neuronal Nicotinic Acetylcholine Receptors | CHRNA2, CHRNA4, CHRNA5 | FFAR1 677/4885FFAR4 988/4885CHRNA7 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.