Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.58 |
| ▸ | SDHA | P31040 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CALML3 | P27482 | 1/20 | 0.58 |
| ▸ | F10 | P00742 | 2/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3181071 | 0.88 | MAOA (0.63) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL5208261 | 0.88 | MAOA (0.63) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL9550299 | 0.88 | MAOA (0.57) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL9550276 | 0.88 | MAOA (0.57) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL13298924 | 0.88 | MAOA (0.61) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL9550270 | 0.86 | MAOA (0.52) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL9823761 | 0.85 | MAOA (0.65) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6753215 | 0.85 | MAOA (0.51) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL7106545 | 0.84 | MAOA (0.62) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6755472 | 0.84 | MAOA (0.50) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646629-B1 | CYCLOPROPYL GROUP SUBSTITUTED OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | MERCK SHARP & DOHME (US) | 2010-06-23 | — | — | EP | disclosed |