SCHEMBL13337015

SCHEMBL13337015

CC(C)C[C@]1(C(=O)OCCc2ccccc2)CS1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.41
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
CHRM5 P08912 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRM3 P20309 1/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
AKR1B10 O60218 2/20 0.40
AKR1B1 P15121 2/20 0.40
ALDH1A1 P00352 1/20 0.40
TP53 P04637 1/20 0.40
GLA P06280 1/20 0.40
CYP3A4 P08684 1/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8260201 0.86 ALDH1A1 (0.46) TDP1L3MBTL1ALDH1A1MAPK1CTSK
SCHEMBL18656681 0.73 HCAR2 (0.53) HCAR2ESR1ESR2NPC1RAB9A
SCHEMBL10491290 0.73 HCAR2 (0.53) HCAR2ESR1ESR2NPC1RAB9A
SCHEMBL27547309 0.71 HCAR2 (0.54) HCAR2ESR1ESR2NPC1RAB9A
SCHEMBL19105197 0.71 HCAR2 (0.54) HCAR2ESR1ESR2NPC1RAB9A
SCHEMBL114275 0.71 HCAR2 (0.54) HCAR2ESR1ESR2NPC1RAB9A
SCHEMBL114173 0.70 TDP1 (0.58) HCAR2ESR1ESR2NPC1RAB9A
SCHEMBL8391955 0.69 HCAR2 (0.49) HCAR2ESR1ESR2CHRM5CHRM1
SCHEMBL16672966 0.69 HCAR2 (0.49) HCAR2ESR1ESR2NPC1RAB9A
SCHEMBL872142 0.69 HCAR2 (0.59) HCAR2ESR1ESR2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2199300-A2 Peptidic compounds The University Of Wollongong (AU) 2010-06-23 EP disclosed