SCHEMBL13338757

SCHEMBL13338757

Cc1cccc(N(c2nccc3ccccc23)C(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.41
SIGMAR1 Q99720 1/20 0.40
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.37
POLB P06746 1/20 0.37
RAB9A P51151 1/20 0.37
CSF1R P07333 3/20 0.36
EGFR P00533 2/20 0.36
DRD1 P21728 1/20 0.36
LMNA P02545 1/20 0.35
CLK1 P49759 1/20 0.35
CLK2 P49760 1/20 0.35
DYRK1A Q13627 1/20 0.35
CLK4 Q9HAZ1 1/20 0.35
DYRK1B Q9Y463 1/20 0.35
F12 P00748 1/20 0.35
PLAU P00749 1/20 0.35
NCF1 P14598 1/20 0.35
NOS3 P29474 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13338587 0.89 CYP2A6 (0.44) CYP2A6KMT2AMEN1NPC1POLB
SCHEMBL13338407 0.86 CYP2A6 (0.44) CYP2A6KMT2ANPC1RAB9ALMNA
SCHEMBL31098968 0.86 CYP2A6 (0.44) CYP2A6KMT2ANPC1RAB9ALMNA
SCHEMBL13338522 0.85 CYP2A6 (0.45) CYP2A6NPC1RAB9AEGFRDRD1
SCHEMBL13338449 0.83 KDM4E (0.41) CYP2A6EGFRDRD1LMNAF12
SCHEMBL13338384 0.82 CYP2A6 (0.50) CYP2A6NPC1RAB9ALMNAF12
SCHEMBL13367465 0.82 CSF1R (0.53) CYP2A6SIGMAR1KMT2AMEN1NPC1
SCHEMBL13338488 0.79 CYP2A6 (0.43) CYP2A6SIGMAR1NPC1RAB9ALMNA
SCHEMBL13338472 0.79 SIGMAR1 (0.44) CYP2A6SIGMAR1LMNA
SCHEMBL13432673 0.78 KMT2A (0.48) CYP2A6SIGMAR1KMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OR10J3, OCIAD1, OCIAD2 CYP2A6 2286/4885SIGMAR1 699/4885KMT2A 3622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.