Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3423023 | 0.80 | PDE4B (0.30) | — | |
| SCHEMBL19299872 | 0.68 | KDM4C (0.35) | KDM4CNPC1RAB9AEP300CREBBP | |
| SCHEMBL3522758 | 0.67 | MEN1 (0.35) | KDM4CNPC1RAB9AP2RX3EP300 | |
| SCHEMBL18834301 | 0.67 | P2RX3 (0.40) | P2RX3KMT2A | |
| SCHEMBL9923393 | 0.65 | KDM4C (0.37) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL24967885 | 0.65 | MEN1 (0.31) | KDM4CNPC1RAB9AMEN1KMT2A | |
| SCHEMBL19253491 | 0.64 | KDM4C (0.34) | KDM4CNPC1RAB9AEP300CREBBP | |
| SCHEMBL17150168 | 0.64 | KDM4E (0.43) | KDM4CNPC1RAB9AEP300CREBBP | |
| SCHEMBL24195847 | 0.64 | KDM4C (0.39) | KDM4CNPC1RAB9AP2RX3EP300 | |
| SCHEMBL21802183 | 0.63 | MEN1 (0.39) | RAB9AEP300CREBBPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718781-B2 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-05-18 | — | — | US | disclosed |
| US-7718781-B2 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-05-18 | — | — | US | disclosed |