SCHEMBL13340331

SCHEMBL13340331

c1ccc(-c2cc(-c3ccc(N4c5ccccc5Cc5ccccc54)cc3)c3c4ccccc4c4ccccc4c3c2-c2ccc(N3CCCc4ccccc43)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 2/20 0.35
TP53 P04637 1/20 0.32
LMNA P02545 2/20 0.32
RECQL P46063 1/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32
EED O75530 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
AKT1 P31749 1/20 0.31
PIK3CA P42336 1/20 0.31
HPGD P15428 1/20 0.31
KDM4E B2RXH2 1/20 0.31
CYP1A2 P05177 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ALDH1A1 P00352 1/20 0.31
OPRD1 P41143 1/20 0.31
OPRK1 P41145 1/20 0.31
SCN9A Q15858 1/20 0.31
ROCK1 Q13464 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13340325 0.93 OPRM1 (0.39) OPRM1TP53LMNARECQLRXRA
SCHEMBL13340298 0.93 OPRM1 (0.39) OPRM1TP53LMNARECQLRXRA
SCHEMBL13340252 0.93 OPRM1 (0.39) OPRM1TP53LMNARECQLRXRA
SCHEMBL13340327 0.89 HPGD (0.38) L3MBTL1HPGDKDM4EALDH1A1
SCHEMBL13340297 0.89 HPGD (0.38) L3MBTL1HPGDKDM4EALDH1A1
SCHEMBL13340251 0.89 HPGD (0.38) L3MBTL1HPGDKDM4EALDH1A1
SCHEMBL13340334 0.88 OPRM1 (0.33) OPRM1TP53LMNAEEDHPGD
SCHEMBL13339228 0.87 OPRM1 (0.38) OPRM1TP53LMNARECQLRXRA
SCHEMBL13340302 0.86 HSD17B3 (0.33) L3MBTL1HPGDKDM4EALDH1A1
SCHEMBL13340269 0.86 OPRM1 (0.35) OPRM1TP53LMNARECQLRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-05-06 US disclosed
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100108997-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OR10J3, OCIAD1, OCIAD2 OPRM1 9/4885TP53 4247/4885LMNA 4085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.