Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SLC33A1 | O00400 | 3/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1892606 | 0.92 | PPARG (0.50) | PPARGKCNH2SLC33A1AGTR1 | |
| SCHEMBL12348977 | 0.88 | SLC33A1 (0.54) | PPARGSLC33A1 | |
| SCHEMBL1889160 | 0.88 | SLC33A1 (0.51) | PPARGSLC33A1AGTR1 | |
| SCHEMBL1891428 | 0.87 | PPARG (0.52) | PPARGSLC33A1AGTR1 | |
| SCHEMBL1896260 | 0.87 | SLC33A1 (0.49) | PPARGSLC33A1AGTR1 | |
| SCHEMBL12349046 | 0.86 | SLC33A1 (0.52) | PPARGSLC33A1 | |
| SCHEMBL1893799 | 0.86 | APLNR (0.38) | — | |
| SCHEMBL1894374 | 0.86 | PPARG (0.50) | PPARGKCNH2SLC33A1AGTR1 | |
| SCHEMBL1890468 | 0.86 | SLC33A1 (0.52) | PPARGSLC33A1AGTR1 | |
| SCHEMBL1885811 | 0.85 | PPARG (0.56) | PPARGSLC33A1AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113780-A1 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2010-05-06 | — | — | US | disclosed |
| US-20100113780-A1 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113780-A1 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | C1R, C1S, C3AR1 | PPARG 3043/4885KCNH2 383/4885SLC33A1 817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.