Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | PHPT1 | Q9NRX4 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | MED25 | Q71SY5 | 1/20 | 0.56 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.56 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 4/20 | 0.55 |
| ▸ | RECQL | P46063 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Psoromic Acid SCHEMBL2113679 | 0.86 | MAPT (0.71) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| Psoromic Acid SCHEMBL29934794 | 0.86 | MAPT (0.71) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2114540 | 0.85 | KDM4E (0.58) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2111729 | 0.85 | MEN1 (0.58) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2114883 | 0.83 | KDM4E (0.56) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2112898 | 0.83 | MEN1 (0.56) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2113411 | 0.82 | KDM4E (0.56) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2113620 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2112509 | 0.81 | KDM4E (0.54) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2113036 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2199295-A1 | COMPOUNDS WITH 7-MEMBER CYCLE AND THE PHARMACEUTICAL USE THEREOF FOR PREVENTING AND TREATING DIABETES AND METABOLISM SYNDROME | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2010-06-23 | — | — | EP | disclosed |