SCHEMBL1334409

SCHEMBL1334409

Cc1ccc(N(c2ccc(C)cc2)c2ccc(Cc3ccc(N(c4ccc(C)cc4)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
TSHR P16473 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
CYP3A4 P08684 1/20 0.54
MAPK1 P28482 1/20 0.54
IDO1 P14902 1/20 0.44
SRD5A2 P31213 1/20 0.44
CYP2C19 P33261 1/20 0.43
CYP1A2 P05177 1/20 0.41
CYP2A6 P11509 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
ACHE P22303 1/20 0.40
CNR2 P34972 3/20 0.40
AGXT P21549 2/20 0.39
LTA4H P09960 1/20 0.39
CNR1 P21554 1/20 0.39
DAO P14920 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6004796 1.00 ALDH1A1 (0.54) ALDH1A1TSHRTDP1CYP3A4MAPK1
SCHEMBL13884016 0.93 ALDH1A1 (0.48) ALDH1A1TSHRTDP1CYP3A4MAPK1
SCHEMBL13884029 0.93 ALDH1A1 (0.48) ALDH1A1TSHRTDP1CYP3A4MAPK1
SCHEMBL14108153 0.91 CYP2C19 (0.57) ALDH1A1TSHRTDP1CYP3A4MAPK1
SCHEMBL10071629 0.91 CYP2C19 (0.52) ALDH1A1TSHRTDP1CYP3A4MAPK1
SCHEMBL19313224 0.91 CYP2C19 (0.52) ALDH1A1TSHRTDP1CYP3A4MAPK1
SCHEMBL14342508 0.89 ESR1 (0.56) ALDH1A1TSHRTDP1CYP3A4MAPK1
SCHEMBL26052510 0.89 CYP2C19 (0.55) ALDH1A1TSHRTDP1CYP3A4MAPK1
SCHEMBL13884025 0.88 ALDH1A1 (0.43) ALDH1A1TSHRTDP1CYP3A4MAPK1
Diphenylmethane SCHEMBL15275153 0.87 CYP2C19 (0.57) ALDH1A1TSHRTDP1CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050142473-A1 For use in electrophotography; electroconducting protective layer includes dispersed tin oxide particles formed on the compliant layer EASTMAN KODAK COMPANY 2005-06-30 US claimed
US-6541171-B1 Primary image-forming member roller for a photographic color machine having a rigid cylindrical core and a compliant layer surrounded by a flexible replaceable removable sleeve of anendless tubular belt; nonadhesive; accuracy; copiers NEXPRESS SOLUTIONS LLC 2003-04-01 US claimed
US-4127412-A BIS(AMINOARYL)ALKANES EASTMAN KODAK COMPANY (US) 1978-11-28 US claimed
US-20190115538-A1 ORGANIC LIGHT-EMITTING DEVICE AND FLAT DISPLAY APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-04-18 US disclosed
US-20170062718-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-03-02 US disclosed
US-20170062718-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-03-02 US disclosed
EP-2019339-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY, METHOD FOR PRODUCING CONDUCTIVE BASE, IMAGE FORMING DEVICE, AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEM CORP (JP) 2015-08-12 EP disclosed
US-8906586-B2 Coating fluid for photosensitive-layer formation, process for producing the same, photoreceptor produced with the coating fluid, image-forming apparatus employing the photoreceptor, and electrophotographic cartridge employing the photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2014-12-09 US disclosed
EP-2196859-B1 Coating fluid for forming undercoat layer and electrographic photoreceptor having undercoat layer formed by applying said coating fluid MITSUBISHI CHEM CORP (JP) 2014-01-22 EP disclosed
EP-1813991-B1 COATING LIQUID FOR UNDERCOATING LAYER FORMATION, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR HAVING UNDERCOATING LAYER FORMED BY COATING OF SAID COATING LIQUID MITSUBISHI CHEM CORP (JP) 2013-07-03 EP disclosed
EP-2019338-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY, IMAGE FORMING DEVICE, AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEM CORP (JP) 2013-07-03 EP disclosed
US-20030044704-A1 Sleeved photoconductive member and method of making EASTMAN KODAK COMPANY 2003-03-06 US disclosed
US-6377772-B1 Double-sleeved electrostatographic roller and method of using NEXPRESS SOLUTIONS LLC 2002-04-23 US disclosed
EP-1195649-A2 Sleeved photoconductive member and method of making NexPress Solutions LLC (US) 2002-04-10 EP disclosed
US-5124218-A Photoconductor element for making multiple copies and process for using same EASTMAN KODAK COMPANY (US) 1992-06-23 US disclosed
US-5053304-A Photoconductor element for making multiple copies and process for using same EASTMAN KODAK COMPANY (US) 1991-10-01 US disclosed
EP-0115198-B1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTIVE ELEMENTS TOMOEGAWA PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-03-11 EP disclosed
US-4539282-A SENSITIZED ZINC OXIDE, POLYCARBONATE BINDER AND AROMATIC DIAMINE TOMOEGAWA PAPER MANUFACTURING COMPANY LIMITED (JP) 1985-09-03 US disclosed
EP-0115198-A1 Electrophotographic photoconductive elements TOMOEGAWA PAPER MANUFACTURING COMPANY LIMITED (JP) 1984-08-08 EP disclosed
US-4127412-A BIS(AMINOARYL)ALKANES EASTMAN KODAK COMPANY (US) 1978-11-28 US disclosed