Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.44 |
| ▸ | OGA | O60502 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31164729 | 0.82 | OGA (0.50) | OGA | |
| SCHEMBL15880246 | 0.76 | OGA (0.51) | OGA | |
| SCHEMBL21800245 | 0.75 | OGA (0.53) | OGA | |
| SCHEMBL12199723 | 0.72 | OGA (0.50) | HRH3OGAKCNH2 | |
| SCHEMBL12199720 | 0.72 | HRH3 (0.47) | HRH3KCNH2 | |
| SCHEMBL176096 | 0.71 | HRH3 (0.37) | HRH3KCNH2 | |
| SCHEMBL3441463 | 0.66 | HRH3 (0.35) | HRH3OGA | |
| SCHEMBL12245051 | 0.66 | HRH3 (0.51) | HRH3 | |
| SCHEMBL8111728 | 0.65 | SMN1; SMN2 (0.44) | OGA | |
| SCHEMBL23138292 | 0.65 | PDCD1 (0.39) | OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010071822-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2010-06-24 | — | — | WO | disclosed |