Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12199713 | 0.76 | SLC27A1 (0.47) | — | |
| SCHEMBL13344486 | 0.72 | HRH3 (0.44) | HRH3KCNH2 | |
| SCHEMBL12245061 | 0.70 | HRH3 (0.59) | HRH3 | |
| SCHEMBL12245068 | 0.70 | HRH3 (0.59) | HRH3 | |
| SCHEMBL12199719 | 0.70 | GRAMD1A (0.44) | HRH3 | |
| SCHEMBL30359087 | 0.69 | CHI3L1 (0.44) | HRH3 | |
| SCHEMBL233663 | 0.68 | NPC1 (0.51) | HRH3 | |
| SCHEMBL13711959 | 0.68 | NPC1 (0.51) | HRH3 | |
| SCHEMBL160290 | 0.67 | NPC1 (0.53) | HRH3 | |
| Bromide SCHEMBL6317924 | 0.65 | NPC1 (0.51) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110245267-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING PLOUGH CORPORATION (US) | 2011-10-06 | — | — | US | disclosed |
| US-20110245267-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING PLOUGH CORPORATION (US) | 2011-10-06 | — | — | US | disclosed |
| WO-2010071822-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES AND METHODS OF USE THEREOF | SCHERING CORPORATION (US) | 2010-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245267-A1 | PIPERIDINE AND PIPERAZINE DERIVATIVES AND METHODS OF USE THEREOF | GPR119, GID4, IL5 | HRH3 287/4885KCNH2 916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.