Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.49 |
| ▸ | ITGAV | P06756 | 16/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13369312 | 0.93 | ITGB3 (0.49) | ITGB3ITGAVITGA2B | |
| SCHEMBL13369222 | 0.88 | ITGB3 (0.52) | ITGB3ITGAVITGA2B | |
| SCHEMBL13344587 | 0.86 | ITGB3 (0.58) | ITGB3ITGAVITGA2B | |
| SCHEMBL5755977 | 0.84 | ITGB3 (0.60) | ITGB3ITGAVITGA2B | |
| SCHEMBL3536943 | 0.84 | ITGB3 (0.53) | ITGB3ITGAVITGA2B | |
| SCHEMBL13344598 | 0.82 | ITGB3 (0.57) | ITGB3ITGAVITGA2B | |
| SCHEMBL29262108 | 0.81 | ITGB3 (0.57) | ITGB3ITGAVITGA2B | |
| SCHEMBL13344627 | 0.81 | ITGB3 (0.57) | ITGB3ITGAVITGA2B | |
| SCHEMBL3545917 | 0.81 | ITGB3 (0.53) | ITGB3ITGAVITGA2B | |
| SCHEMBL13344621 | 0.81 | ITGB3 (0.52) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718673-B2 | Isonipecotamides for the treatment of integrin-mediated disorders | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2010-05-18 | — | — | US | disclosed |