Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13344906 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL8905004 | 0.84 | MEN1 (0.49) | ALDH1A1MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL8905152 | 0.84 | MEN1 (0.49) | ALDH1A1MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL8905280 | 0.84 | MEN1 (0.49) | ALDH1A1MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL15574708 | 0.81 | MEN1 (0.45) | ALDH1A1MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL15573155 | 0.81 | MEN1 (0.48) | ALDH1A1MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL4078443 | 0.81 | MEN1 (0.42) | ALDH1A1MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL15575173 | 0.81 | MEN1 (0.42) | ALDH1A1MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL12747477 | 0.81 | MEN1 (0.48) | ALDH1A1MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL15615492 | 0.81 | MEN1 (0.45) | ALDH1A1MEN1KMT2AMAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069979-A1 | PYRAN DERIVATIVES AS CCR3 MODULATORS | NYCOMED GMBH (DE) | 2010-06-24 | — | — | WO | disclosed |