Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 3/20 | 0.44 |
| ▸ | TREH | O43280 | 1/20 | 0.37 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.34 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.34 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25871286 | 1.00 | LGALS3 (0.44) | LGALS3TREHLGALS1LGALS9LGALS8 | |
| SCHEMBL13295915 | 1.00 | LGALS3 (0.44) | LGALS3TREHLGALS1LGALS9LGALS8 | |
| SCHEMBL25672308 | 1.00 | LGALS3 (0.44) | LGALS3TREHLGALS1LGALS9LGALS8 | |
| SCHEMBL14613514 | 1.00 | LGALS3 (0.44) | LGALS3TREHLGALS1LGALS9LGALS8 | |
| SCHEMBL24916892 | 1.00 | LGALS3 (0.44) | LGALS3TREHLGALS1LGALS9LGALS8 | |
| SCHEMBL15966159 | 1.00 | LGALS3 (0.44) | LGALS3TREHLGALS1LGALS9LGALS8 | |
| SCHEMBL23705209 | 1.00 | LGALS3 (0.44) | LGALS3TREHLGALS1LGALS9LGALS8 | |
| SCHEMBL16155530 | 1.00 | LGALS3 (0.44) | LGALS3TREHLGALS1LGALS9LGALS8 | |
| SCHEMBL13295952 | 1.00 | LGALS3 (0.44) | LGALS3TREHLGALS1LGALS9LGALS8 | |
| SCHEMBL12929237 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069979-A1 | PYRAN DERIVATIVES AS CCR3 MODULATORS | NYCOMED GMBH (DE) | 2010-06-24 | — | — | WO | disclosed |