Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.72 |
| ▸ | LMNA | P02545 | 6/20 | 0.72 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | PGR | P06401 | 3/20 | 0.72 |
| ▸ | AR | P10275 | 3/20 | 0.72 |
| ▸ | STS | P08842 | 3/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.72 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.72 |
| ▸ | SHBG | P04278 | 2/20 | 0.72 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.72 |
| ▸ | SNCA | P37840 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14395341 | 1.00 | ESR1 (0.72) | ESR1LMNAESR2KMT2AMEN1 | |
| SCHEMBL5158676 | 1.00 | ESR1 (0.72) | ESR1LMNAESR2KMT2AMEN1 | |
| SCHEMBL11776204 | 0.94 | ESR1 (0.65) | ESR1LMNAESR2KMT2AMEN1 | |
| SCHEMBL5157957 | 0.91 | ESR1 (0.69) | ESR1LMNAESR2KMT2AMEN1 | |
| SCHEMBL5158101 | 0.89 | ESR1 (0.70) | ESR1LMNAESR2KMT2AMEN1 | |
| SCHEMBL11783196 | 0.88 | STS (0.69) | ESR1LMNAESR2KMT2AMEN1 | |
| SCHEMBL15307735 | 0.87 | ESR1 (0.56) | ESR1LMNAESR2KMT2AMEN1 | |
| SCHEMBL11780732 | 0.87 | STS (0.67) | ESR1LMNAESR2KMT2AMEN1 | |
| SCHEMBL17817385 | 0.87 | STS (0.67) | ESR1LMNAESR2KMT2AMEN1 | |
| SCHEMBL11788270 | 0.87 | STS (0.67) | ESR1LMNAESR2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2202240-A1 | Compound | Sterix Limited (GB) | 2010-06-30 | — | — | EP | disclosed |