Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.72 |
| ▸ | LMNA | P02545 | 6/20 | 0.72 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | PGR | P06401 | 3/20 | 0.72 |
| ▸ | AR | P10275 | 3/20 | 0.72 |
| ▸ | STS | P08842 | 3/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.72 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.72 |
| ▸ | SHBG | P04278 | 2/20 | 0.72 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.72 |
| ▸ | SNCA | P37840 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13345142 | 1.00 | ESR1 (0.72) | ESR1LMNAESR2KMT2AMEN1 | |
| SCHEMBL14395341 | 1.00 | ESR1 (0.72) | ESR1LMNAESR2KMT2AMEN1 | |
| SCHEMBL11776204 | 0.94 | ESR1 (0.65) | ESR1LMNAESR2KMT2AMEN1 | |
| SCHEMBL5157957 | 0.91 | ESR1 (0.69) | ESR1LMNAESR2KMT2AMEN1 | |
| SCHEMBL5158101 | 0.89 | ESR1 (0.70) | ESR1LMNAESR2KMT2AMEN1 | |
| SCHEMBL11783196 | 0.88 | STS (0.69) | ESR1LMNAESR2KMT2AMEN1 | |
| SCHEMBL15307735 | 0.87 | ESR1 (0.56) | ESR1LMNAESR2KMT2AMEN1 | |
| SCHEMBL11780732 | 0.87 | STS (0.67) | ESR1LMNAESR2KMT2AMEN1 | |
| SCHEMBL17817385 | 0.87 | STS (0.67) | ESR1LMNAESR2KMT2AMEN1 | |
| SCHEMBL11788270 | 0.87 | STS (0.67) | ESR1LMNAESR2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244458-B1 | WEIGHT PROMOTING COMPOSITION, METHOD, AND PRODUCT | PHERIN PHARM INC (US) | 2007-10-03 | — | — | EP | claimed |
| US-6555531-B1 | Administering pregnanes such as 21-methyl-19-norpregna-1,3,5(10)-trien-3-ol; treating cachexia, eating disorders, AIDS, and giving to athletes | PHERIN PHARMACEUTICALS, INC. | 2003-04-29 | — | — | US | claimed |
| US-5792757-A | ANTIFERTILITY AGENTS, ANXIOLYTIC AGENTS | PHERIN PHARMACEUTICALS (US) | 1998-08-11 | — | — | US | claimed |
| US-3946052-A | 19-Norpregna- 1,3,5(10)-trien-3-ol and loweralkyl homologs thereof having postcoital antifertility activity | STANFORD RESEARCH INSTITUTE (US) | 1976-03-23 | — | — | US | claimed |
| EP-1244458-B1 | WEIGHT PROMOTING COMPOSITION, METHOD, AND PRODUCT | PHERIN PHARM INC (US) | 2007-10-03 | — | — | EP | disclosed |
| EP-1405860-B1 | Estrone sulfamate inhibitors of estrone sulfatase, and associated pharmaceutical compositions and methods of use | STANFORD RES INST INT (US) | 2007-02-14 | — | — | EP | disclosed |
| EP-1405860-A1 | Estrone sulfamate inhibitors of estrone sulfatase, and associated pharmaceutical compositions and methods of use | SRI INTERNATIONAL (US) | 2004-04-07 | — | — | EP | disclosed |
| EP-0830369-B1 | NOR-PREGNANES FOR INDUCING HYPOTHALAMIC EFFECTS | PHERIN PHARM INC (US) | 2003-05-14 | — | — | EP | disclosed |
| US-6555531-B1 | Administering pregnanes such as 21-methyl-19-norpregna-1,3,5(10)-trien-3-ol; treating cachexia, eating disorders, AIDS, and giving to athletes | PHERIN PHARMACEUTICALS, INC. | 2003-04-29 | — | — | US | disclosed |
| EP-1244458-A2 | WEIGHT PROMOTING COMPOSITION, METHOD, AND PRODUCT | Pherin Pharmaceuticals, Inc. (US) | 2002-10-02 | — | — | EP | disclosed |
| EP-0416814-B1 | Antibacterial cephalosporin derivatives | PFIZER (US) | 2002-04-24 | — | — | EP | disclosed |
| WO-2001049280-A2 | WEIGHT PROMOTING COMPOSITION, METHOD, AND PRODUCT | PHERIN PHARMACEUTICALS, INC. (US) | 2001-07-12 | — | — | WO | disclosed |
| WO-1999033858-A2 | ESTRONE SULFAMATE INHIBITORS OF ESTRONE SULFATASE, AND ASSOCIATED PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE | SRI INTERNATIONAL (US) | 1999-07-08 | — | — | WO | disclosed |
| US-5861388-A | TREATMENT OF ESTROGEN DEPENDENT DISORDERS AS FOR EXAMPLEBREAST CANCER | SRI INTERNATIONAL (US) | 1999-01-19 | — | — | US | disclosed |
| WO-1998032763-A1 | STEROID INHIBITORS OF ESTRONE SULFATASE, AND ASSOCIATED PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE | SRI INTERNATIONAL (US) | 1998-07-30 | — | — | WO | disclosed |
| US-5763432-A | TREATMENT OF ESTROGEN-DEPENDENT DISORDERS | SRI INTERNATIONAL (US) | 1998-06-09 | — | — | US | disclosed |
| US-4059575-A | Process for the preparation of 17(20)ene-21-steroid aldehydes | RESEARCH CORPORATION (US) | 1977-11-22 | — | — | US | disclosed |
| US-3946052-A | 19-Norpregna- 1,3,5(10)-trien-3-ol and loweralkyl homologs thereof having postcoital antifertility activity | STANFORD RESEARCH INSTITUTE (US) | 1976-03-23 | — | — | US | disclosed |
| US-3946052-A | 19-Norpregna- 1,3,5(10)-trien-3-ol and loweralkyl homologs thereof having postcoital antifertility activity | STANFORD RESEARCH INSTITUTE (US) | 1976-03-23 | — | — | US | disclosed |
| US-3946052-A | 19-Norpregna- 1,3,5(10)-trien-3-ol and loweralkyl homologs thereof having postcoital antifertility activity | STANFORD RESEARCH INSTITUTE (US) | 1976-03-23 | — | — | US | disclosed |