Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST6GAL1 | P15907 | 2/20 | 0.44 |
| ▸ | ST3GAL1 | Q11201 | 2/20 | 0.44 |
| ▸ | ST3GAL3 | Q11203 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.43 |
| ▸ | OSBP | P22059 | 3/20 | 0.43 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.41 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.41 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1878894 | 0.95 | CYP46A1 (0.47) | ST6GAL1ST3GAL1ST3GAL3NR1H3OSBP | |
| SCHEMBL13311391 | 0.95 | CYP46A1 (0.47) | ST6GAL1ST3GAL1ST3GAL3NR1H3OSBP | |
| SCHEMBL1878892 | 0.95 | CYP46A1 (0.47) | ST6GAL1ST3GAL1ST3GAL3NR1H3OSBP | |
| SCHEMBL12639020 | 0.95 | CYP46A1 (0.47) | ST6GAL1ST3GAL1ST3GAL3NR1H3OSBP | |
| SCHEMBL1881130 | 0.90 | OSBP (0.46) | ST6GAL1ST3GAL1ST3GAL3NR1H3OSBP | |
| SCHEMBL1881129 | 0.90 | OSBP (0.46) | ST6GAL1ST3GAL1ST3GAL3NR1H3OSBP | |
| SCHEMBL12639010 | 0.90 | OSBP (0.46) | ST6GAL1ST3GAL1ST3GAL3NR1H3OSBP | |
| SCHEMBL12639002 | 0.90 | OSBP (0.46) | ST6GAL1ST3GAL1ST3GAL3NR1H3OSBP | |
| SCHEMBL13311388 | 0.90 | OSBP (0.46) | ST6GAL1ST3GAL1ST3GAL3NR1H3OSBP | |
| SCHEMBL1879721 | 0.90 | OSBP (0.46) | ST6GAL1ST3GAL1ST3GAL3NR1H3OSBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010071772-A2 | SYNTHESIS OF 3B-AMINO-5-CHOLESTENE AND RELATED 3B-HALIDES INVOLVING I-STEROID AND RETRO-I-STEROID REARRANGEMENTS | THE PENN STATE RESEARCH FOUNDATION (US) | 2010-06-24 | — | — | WO | disclosed |