Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.45 |
| ▸ | ATP4A | P20648 | 1/20 | 0.45 |
| ▸ | ATP4B | P51164 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | DDX3X | O00571 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2887195 | 0.88 | L3MBTL1 (0.62) | L3MBTL1ALOX5ALDH1A1TRPM8CDC7 | |
| SCHEMBL13345947 | 0.84 | RARB (0.53) | L3MBTL1TSHRTDP1ALOX5CYP3A4 | |
| SCHEMBL13345606 | 0.82 | L3MBTL1 (0.51) | L3MBTL1ALOX5TRPM8 | |
| SCHEMBL2482853 | 0.79 | L3MBTL1 (0.57) | L3MBTL1ALOX5ALDH1A1TRPM8CDC7 | |
| SCHEMBL12030404 | 0.78 | L3MBTL1 (0.55) | L3MBTL1ALOX5ALDH1A1TRPM8 | |
| SCHEMBL12049697 | 0.76 | CDC7 (0.64) | L3MBTL1ALOX5ALDH1A1TRPM8CDC7 | |
| SCHEMBL2483841 | 0.75 | L3MBTL1 (0.59) | L3MBTL1ALOX5ALDH1A1TRPM8CDC7 | |
| SCHEMBL22939973 | 0.75 | L3MBTL1 (0.62) | L3MBTL1ALOX5ALDH1A1TRPM8CDC7 | |
| SCHEMBL12049696 | 0.75 | L3MBTL1 (0.58) | L3MBTL1ALOX5ALDH1A1TRPM8CDC7 | |
| SCHEMBL12049565 | 0.74 | L3MBTL1 (0.64) | L3MBTL1ALOX5ALDH1A1TRPM8CDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010071853-A1 | THIAZOLOPYRIDINE SIRTUIN MODULATING COMPOUNDS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2010-06-24 | — | — | WO | disclosed |