Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.42 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26656112 | 0.88 | CTSK (0.43) | CTSKCTSSPREPCA1CA2 | |
| SCHEMBL15228678 | 0.88 | CTSK (0.43) | CTSKCTSSPREPCA1CA2 | |
| SCHEMBL20701884 | 0.88 | CTSK (0.43) | CTSKCTSSPREPCA1CA2 | |
| SCHEMBL15228429 | 0.88 | CTSK (0.43) | CTSKCTSSPREPCA1CA2 | |
| SCHEMBL1334871 | 0.84 | CTSK (0.40) | CTSKCTSSPREPCA1CA2 | |
| SCHEMBL22527160 | 0.84 | CTSK (0.40) | CTSKCTSSPREPCA1CA2 | |
| SCHEMBL15228716 | 0.84 | CTSK (0.40) | CTSKCTSSPREPCA1CA2 | |
| SCHEMBL15228718 | 0.84 | CTSK (0.40) | CTSKCTSSPREPCA1CA2 | |
| SCHEMBL7056042 | 0.84 | CTSK (0.40) | CTSKCTSSPREPCA1CA2 | |
| SCHEMBL26207740 | 0.84 | CTSK (0.40) | CTSKCTSSPREPCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110282081-A1 | Methods of Preparing 1-Deoxy-Sphingoid Bases and Derivatives Thereof | EMORY UNIVERSITY (US) | 2011-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110282081-A1 | Methods of Preparing 1-Deoxy-Sphingoid Bases and Derivatives Thereof | DEGS1, SPHK1, SPHK2 | CTSK 2820/4885CTSS 2526/4885PREP 2806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.